SYNTHESES OF HINDERED ALKYL PHOSPHONATES AND PHOSPHONIC & PHOSPHINIC ACIDS

作     者：Wen Xiang HU Cheng Ye YUAN Shu Shen LI 

作者机构：Shanghai Institute of Organic ChemistryChinese Academy of SciencesShanghai 200032 

出 版 物：《Chinese Chemical Letters》 (中国化学快报(英文版))

年 卷 期：1992年第3卷第3期

页      面：167-170页

核心收录：

学科分类：07[理学] 0703[理学-化学] 

基　　金：Project Supported by National Science Foundation of China 

主　　题：SYNTHESES OF HINDERED ALKYL PHOSPHONATES AND PHOSPHONIC PHOSPHINIC ACIDS 

摘      要：A series of di-n-hexyl alkyl phosphonates with bulky substituent on phosphorus was synthesized by PTC P-alkylation using crown *** saponification of the resulting di-n-hexyl alkylphosphonates in the presence of crown ether or quaternary ammonium halide, corresponding mono-hexyl esters of alkyl phosphonic acids were *** wave, as we found, can catalyze the reaction between dialkyl phosphite & metallic sodium and hydrolysis of dihexyl alkyl phosphonates.A series of di-t-alkyl phosphinic acids were synthesized by the reaction of Grignard reagent with PCl_3 followed by oxidation with 30% H_2O_*** was found that the reaction between dibutyl phosphite and Grignard reagent of t-alkyl chloride is a new synthetic method for the preparation of mono-esters of highly hindered alkyl phosphonic acids.