Very low calorie ketogenic diet and common rheumatic disorders:A case report

作     者：Mariangela Rondanelli Zaira Patelli Clara Gasparri Francesca Mansueto Cinzia Ferraris Mara Nichetti Tariq A Alalwan Ignacio Sajoux Roberto Maugeri Simone Perna 

作者机构：Department of Public HealthExperimental and Forensic MedicineUnit of Human and Clinical NutritionIRCCS Mondino FoundationPavia 27100Italy Endocrinology and Nutrition UnitAzienda di Servizi alla Persona"Istituto Santa Margherita"University of PaviaPavia 27100Italy Food Education and Sport Nutrition LaboratoryDepartment of Public HealthExperimental and Forensic MedicineUniversity of PaviaPavia 27100Italy Department of BiologyCollege of ScienceUniversity of BahrainSakhir 32038Bahrain Chief Scientific OfficeMedical Department Pronokal GroupBarcelona 08001Spain Medical DirectionPronoKal GroupSavigliano 12038Italy 

出 版 物：《World Journal of Clinical Cases》 (世界临床病例杂志)

年 卷 期：2023年第11卷第9期

页      面：1985-1991页

核心收录：

学科分类：1002[医学-临床医学] 1010[医学-医学技术（可授医学、理学学位）] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 100215[医学-康复医学与理疗学] 10[医学] 

主　　题：Very low calorie ketogenic diet Inflammation PNK 

摘      要：BACKGROUND The scientific literature provides evidence that nutritional ketosis can be an important support in the treatment of pathologies in which inflammation is present,as recent studies have shown that ketone bodies have anti-inflammatory activity in numerous diseases,including rheumatic *** report the case of a 22-year-old woman with class I obesity and juvenile idiopathic arthritis who started treatment with a very low calorie ketogenic diet(VLCKD).CASE SUMMARY The patient was a 22-year-old woman diagnosed with juvenile idiopathic arthritis at age 4 years and with a body mass index(BMI)of 30.8 kg/m2,waist circumference(WC)80 cm,fat mass(FM)28.1 kg,free FM 45.7 kg,and visceral adipose tissue(VAT)3.5 kg,assessed on bioimpedance *** was treated using a commercial VLCKD weight-loss program(PNK®method);this program provides high-biological-value protein preparations and natural *** protein preparation contains 15 g protein,4 g carbohydrate,3 g fat,and 50 mg omega-3 docosahexaenoic acid,with an energy content of 90–120 *** four months on the program,the BMI was 28.6 kg/m2,WC 73 cm,FM 23.2 kg,free FM 41.9 kg,and VAT 2.9 *** VLCKD enabled the patient to reach her target weight and to reduce her joint pain and *** inflammatory indices also normalized.