Two new benzopyran derivatives from Gouania leptostachya DC. var. tonkinensis Pitard.

作     者：Chong Yao Shu Jie Zhang Zheng Zhong Bai Tong Zhou Li Jiang Xua 

作者机构：Huzhou Central Hospital Huzhou 313000 China Heilongjiang University of Chinese Medicine Harbin 150040 China Heilongjiang Institute for Drug Control Harbin 150001 China State Key Laboratory of Drug Research Shanghai Institute of Materia Medica Shanghai 201203 China Received 27 May 2010 

出 版 物：《Chinese Chemical Letters》 (中国化学快报（英文版）)

年 卷 期：2011年第22卷第2期

页      面：175-177页

核心收录：

学科分类：1007[医学-药学(可授医学、理学学位)] 09[农学] 0904[农学-植物保护] 0703[理学-化学] 10[医学] 

基　　金：the National Science & Technology Major Project "Key New Drug Creation and Manufacturing Program" China(No.2009ZX09301-001) 

主　　题：Gouania leptostachya DC.var.tonkinensis Pitard. Benzopyran derivatives α-Glucosidase inhibitory activity 

摘      要：Two new benzopyran derivatives,1-[（rel 2S,3R）-3,5,7-trihydroxy-3,4-dihydro-2H-chromen-2-yl]ethanone（1）,and 1-[（rel 25,35）-3,5,7-trihydroxy-3,4-dihydro-2H-chromen-2-yl]ethanone（2）,along with four known flavonoids,prodelphinidin C,prodelphinidin B3,（-）-epi-gallocatechin and（＋）-gallocatechin,were isolated from the stems of Gouania leptostachya DC.var. tonkinensis Pitard.Their structures were determined on the basis of spectroscopic methods including HR-ESI-MS,1D and 2D NMR.Prodelphinidin C exhibited significant inhibitory activity forα-glucosidase.