Sclerosing cholangitis associated with autoimmune pancreatitis differs from primary sclerosing cholangitis

作     者：Terumi Kamisawa Kensuke Takuma Hajime Anjiki Naoto Egawa Masanao Kurata Goro Honda Kouji Tsuruta 

作者机构：Department of Internal MedicineTokyo Metropolitan Komagome Hospital3-18-22 HonkomagomeBunkyo-kuTokyo 113-8677Japan Department of SurgeryTokyo Metropolitan Komagome Hospital3-18-22 HonkomagomeBunkyo-kuTokyo 113-8677Japan 

出 版 物：《World Journal of Gastroenterology》 (世界胃肠病学杂志（英文版）)

年 卷 期：2009年第15卷第19期

页      面：2357-2360页

核心收录：

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主　　题：Autoimmune pancreatitis IgG4 Primarysclerosing cholangitis Sclerosing cholangitis 

摘      要：AIM:To clarify the characteristic features of biliary le-sions in patients with autoimmune pancreatitis(AIP) and compare them with those of primary sclerosing cholangitis(PSC) .METHODS:The clinicopathological characteristics of 34 patients with sclerosing cholangitis(SC) associated with AIP were compared with those of 4 patients with ***:SC with AIP occurred predominantly in el-derly *** jaundice was the most frequent initial symptom in SC with *** SC patients with AIP had elevated serum IgG4 levels,and sclerosing diseases were more frequent in these *** pa-tients with AIP responded well to steroid ***-mental stenosis of the lower bile duct was observed only in SC patients with AIP,but a beaded and pruned-tree appearance was detected only in PSC *** infi ltration of IgG4-positive plasma cells was de-tected in the bile duct wall and the periportal area,as well as in the pancreas,of SC patients with ***:SC with AIP is distinctly different from *** two diseases can be discriminated based on cholangiopancreatographic findings and serum IgG4 levels.