Role of upper endoscopy in diagnosing opportunistic infections in human immunodeficiency virus-infected patients

作     者：Ana Luiza Werneck-Silva Ivete Bedin Prado 

作者机构：Casa da AIDS-Infectious Disease DivisionSchool of MedicineUniversity of So PauloRua Frei Caneca 255CEP:05403-000So PauloBrazil University of So PauloHospital das Clínicas da FMUSP Av. Ovídio Pires de Campos2256 andar CEP:05403-010So PauloBrazil 

出 版 物：《World Journal of Gastroenterology》 (世界胃肠病学杂志（英文版）)

年 卷 期：2009年第15卷第9期

页      面：1050-1056页

核心收录：

学科分类：1004[医学-公共卫生与预防医学(可授医学、理学学位)] 1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 100401[医学-流行病与卫生统计学] 10[医学] 

主　　题：Human immunodeficiency virus Opportunistic infections Upper gastrointestinal tract Gastrointestinal endoscopy Highly active antiretroviral therapy 

摘      要：Highly active antiretroviral therapy (HAART) has dramatically decreased opportunistic infections (OIs) in human immunodef iciency virus (HIV)-infected patients. However,gastrointestinal disease continues to account for a high proportion of presenting symptoms in these patients. Gastrointestinal symptoms in treated patients who respond to therapy are more likely to the result of drug-induced complications than OI. Endoscopic evaluation of the gastrointestinal tract remains a cornerstone of diagnosis,especially in patients with advanced immunodeficiency,who are at risk for OI. The peripheral blood CD4 lymphocyte count helps to predict the risk of an OI,with the highest risk seen in HIV-infected patients with low CD4 count ( 200 cells/mm3). This review provides an update of the role of endoscopy in diagnosing OI in the upper gastrointestinal tract in HIV-infected patients in the era of HAART.