Control of epileptic activities in a cortex network of multiple coupled neural populations under electromagnetic induction

作     者：Zhongkui SUN Yuanyuan LIU Xiaoli YANG Wei XU Zhongkui SUN;Yuanyuan LIU;Xiaoli YANG;Wei XU

作者机构：School of Mathematics and StatisticsNorthwestern Polytechnical UniversityXi’an 710129China School of Mathematics and StatisticsShaanxi Normal UniversityXi’an 710062China 

出 版 物：《Applied Mathematics and Mechanics(English Edition)》 (应用数学和力学（英文版）)

年 卷 期：2023年第44卷第3期

页      面：499-514页

核心收录：

学科分类：0831[工学-生物医学工程（可授工学、理学、医学学位）] 0710[理学-生物学] 1002[医学-临床医学] 08[工学] 081104[工学-模式识别与智能系统] 0805[工学-材料科学与工程（可授工学、理学学位）] 0811[工学-控制科学与工程] 0702[理学-物理学] 

基　　金：Project supported by the National Natural Science Foundation of China(Nos.11772254 and 11972288) the Innovation Foundation for Doctor Dissertation of Northwestern Polytechnical University of China(No.CX2021106)。 

主　　题：epilepsy electromagnetic induction multiple coupled neural population dynamical transition 

摘      要：Epilepsy is believed to be associated with the abnormal synchronous neuronal activity in the brain,which results from large groups or circuits of neurons.In this paper,we choose to focus on the temporal lobe epilepsy,and establish a cortex network of multiple coupled neural populations to explore the epileptic activities under electromagnetic induction.We demonstrate that the epileptic activities can be controlled and modulated by electromagnetic induction and coupling among regions.In certain regions,these two types of control are observed to show exactly reverse effects.The results show that the strong electromagnetic induction is conducive to eliminating the epileptic seizures.The coupling among regions has a conduction effect that the previous normal background activity of the region gives way to the epileptic discharge,owing to coupling with spike wave discharge regions.Overall,these results highlight the role of electromagnetic induction and coupling among the regions in controlling and modulating epileptic activities,and might provide novel insights into the treatments of epilepsy.