Epidemiological and clinical characteristics of COVID-19 in a Brazilian public hospital

作     者：Fillipe Dantas Pinheiro Luana Weber Lopes Rafael Santos Dantas Miranda Dórea Glauber Rocha Lima Araújo Filipe Antônio França da Silva Breno Bittencourt de Brito Maria Luísa Cordeiro Santos Geovani Moreno Santos Júnior Maria Teresa Araújo de Lorenzo Barcia Renata de Amorim Marques AndréBezerra Botelho Anna Carolina Saúde Dantas Davi Tanajura Costa Adriano Fernandes Teixeira Cláudio Lima Souza Lucas Miranda Marques Guilherme Barretos Campos Márcio Vasconcelos Oliveira Dulciene Maria de Magalhães Queiroz Fabrício Freire de Melo 

作者机构：Instituto Multidisciplinar em SaúdeUniversidade Federal da BahiaVitória da Conquista 45029-094BahiaBrazil Hospital Geral de Vitória da ConquistaVitória da Conquista 45030-160BahiaBrazil Departamento de Ciências da SaúdeUniversidade Estadual do Sudoeste da Bahia(UESB)Vitória da Conquista 45083-900BahiaBrazil Faculdade de MedicinaUniversidade Federal de Minas GeraisBelo Horizonte 31270-901Minas GeraisBrazil 

出 版 物：《World Journal of Clinical Cases》 (世界临床病例杂志)

年 卷 期：2023年第11卷第8期

页      面：1761-1770页

核心收录：

学科分类：1004[医学-公共卫生与预防医学(可授医学、理学学位)] 1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 100401[医学-流行病与卫生统计学] 10[医学] 

基　　金：Supported by FAPEMIG Edital 001/2020-Programa Emergencial de Apoio a Ações de Enfrentamento da Pandemia Causada pelo Novo Coronavírus.FUNDAÇÃO DE AMPAROÀPESQUISA DO ESTADO DA BAHIA–FAPESB,PPSUS-Programa Pesquisa para o SUS-Headline 02/2020,Term of Grant nºSUS0025/2021 Magalhães Queiroz DM,Freire de Melo F,are research fellows of the Conselho Nacional de Desenvolvimento Científico e Tecnológico(CNPq-)–Brazil.Programa Permanecer da Universidade Federal da Bahia.Programa Institucional de Bolsas de Iniciação Científica da Universidade Federal da Bahia(PIBIC-UFBA) 

主　　题：COVID-19 Epidemiology Symptoms Comorbidities Laboratory parameters 

摘      要：BACKGROUND The coronavirus disease 2019(COVID-19)pandemic has become a major health concern *** that context,the understanding of epidemiological and clinical features associated with the disease and its severity is crucial for the establishment of strategies aimed at disease control and *** To describe epidemiological features,signs,symptoms,and laboratory findings among severely ill COVID-19 patients from an inten-sive care unit in northeastern Brazil as well as to evaluate predictor factors for disease *** This is a prospective single-center study that evaluated 115 patients admitted to the intensive care unit in a northeastern Brazilian *** The patients had a median age of 65.60±15.78 *** was the most frequent symptom,affecting 73.9%of the patients,followed by cough(54.7%).Fever was reported in approximately one-third of patients and myalgia in 20.8%of the *** least two comorbidities were found in 41.7%of the patients,and hypertension was the most prevalent(57.3%).In addition,having two or more comorbidities was a predictor of mortality,and lower platelet count was positively associated with *** and vomiting were two symptoms that were predictors of death,and the presence of a cough was a protective *** This is the first report of a negative correlation between cough and death in severely ill severe acute respiratory syndrome coronavirus 2-infected *** associations between comorbidities,advanced age,and low platelet count and the outcomes of the infection were similar to the results of previous studies,highlighting the relevance of these features.