Prevalence of transmitted drug resistance mutations among patients infected with human immunodeficiency virus type 1 (HIV-1) in Henan Province, China

作     者：Jinjin Liu Xiaohua Zhang Mingjie Hou Shuguang Wei Jie Ma Lixia Xu Xuan Yang Yan Sun Chunli Liu Qingxia Zhao Yuqi Huo Jinjin Liu;Xiaohua Zhang;Mingjie Hou;Shuguang Wei;Jie Ma;Lixia Xu;Xuan Yang;Yan Sun;Chunli Liu;Qingxia Zhao;Yuqi Huo

作者机构：Tanslational Medicine Research CenterHenan Infectious Diseases HospitalZhengzhouHenan 450000China Clinic of Infection and ImmunologyHenan Infectious Diseases HospitalZhengzhouHenan 450000China Department of Infectious DiseasesHenan Infectious Diseases HospitalZhengzhouHenan 450000China 

出 版 物：《Chinese Medical Journal》 (中华医学杂志（英文版）)

年 卷 期：2022年第135卷第22期

页      面：2750-2752页

核心收录：

学科分类：1004[医学-公共卫生与预防医学(可授医学、理学学位)] 1002[医学-临床医学] 100401[医学-流行病与卫生统计学] 10[医学] 

基　　金：Co-Sponsored Construction Project of Provincial Medicine and Technique of Henan Province(No. LHGJ20191103)。 

主　　题：patients immunodeficiency Henan 

摘      要：To the Editor:Even with the emergence of highly active antiretroviral therapy,human immunodeficiency virus type 1(HIV-1)remains a serious public health problem worldwide.The widespread use of antiretroviral therapy(ART)has,on the one hand,significantly improved life expectancy in patients infected with HIV-1;on the other hand,it has inevitably brought along with it a difficult problem—viral resistance.Viral resistance is a common phenomenon evolutionarily,particularly in patients with poor adherence and suboptimal drug levels.