Influence of assisted reproductive technology and uterine leiomyoma on pregnancy outcomes in women with adenomyosis

作     者：Yi-Ling Wang Zhao Tian Xiao-Hong Chang Hong-Lan Zhu Heng Cui Yi-Ling Wang;Zhao Tian;Xiao-Hong Chang;Hong-Lan Zhu;Heng Cui

作者机构：Department of Obstetrics and GynecologyPeople's HospitalPeking UniversityBeijing100044China 

出 版 物：《Gynecology and Obstetrics Clinical Medicine》 (妇产科临床医学（英文）)

年 卷 期：2023年第3卷第1期

页      面：56-59页

学科分类：1002[医学-临床医学] 100211[医学-妇产科学] 10[医学] 

基　　金：“Natural Science Foundation of Beijing Municipality”[No:7222206] 

主　　题：Adenomyosis Adverse pregnancy outcomes Assisted reproductive technology Uterine leiomyoma 

摘      要：Aim To assess whether adverse pregnancy outcomes in women with adenomyosis are different according to the method of conception and the concurrent of uterine leiomyoma(UL).Methods We performed a retrospective ***-three singleton pregnancy cases complicated with adenomyosis were included in this *** the study group,15 women became pregnant with assisted reproductive technology(ART)and 21 women combined with *** outcomes were compared between ART and non-ART,UL and non-UL *** The prevalence for such complications as hypertensive disorder complicating pregnancy(HDCP)and postpartum hemorrhage(PPH)were significantly higher in the women conceived by ART(33.3%vs.5.3%,P​=​0.023)and(53.3%vs.23.7%,P​=​0.037),*** women concurrent with UL of which the diameter≥4​cm were more likely to have severe PPH(44.4%vs.0%,P​=​0.021).Conclusion ART may increase the risk of adverse pregnancy outcomes such as HDCP and PPH in women with adenomyosis and UL of which the diameter≥4​cm may further increase the risk of severe PPH.