Designing artificial synthetic promoters for accurate,smart,and versatile gene expression in plants
作者机构：Single Cell Research CenterSchool of Agriculture and BiologyShanghai Jiao Tong UniversityShanghai 200240China Biotechnology Research InstituteChinese Academy of Agricultural SciencesBeijingChina
出 版 物：《Plant Communications》 (植物通讯（英文）)
年 卷 期：2023年第4卷第4期
页 面：12-29页
核心收录：
学科分类：0710[理学-生物学] 071001[理学-植物学] 07[理学]
基 金：funded by Key Research and Development Projects(nos.2018YFA0901000 and 2018YFA0901003) the BIO-Agri.project of SJTU
主 题：plants synthetic promoter cis element gene expression
摘 要：With the development of high-throughput biology techniques and artificial intelligence,it has become increasingly feasible to design and construct artificial biological parts,modules,circuits,and even whole *** overcome the limitations of native promoters in controlling gene expression,artificial promoter design aims to synthesize short,inducible,and conditionally controlled promoters to coordinate the expression of multiple genes in diverse plant metabolic and signaling *** promoters are versatile and can drive gene expression accurately with smart responses;they show potential for enhancing desirable traits in crops,thereby improving crop yield,nutritional quality,and food *** review first illustrates the importance of synthetic promoters,then introduces promoter architecture and thoroughly summarizes advances in synthetic promoter *** to the development of synthetic promoters and future applications of such promoters in synthetic plant biology and crop improvement are also discussed.
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