External electrolyte-free electrochemical one-pot cascade synthesis of 4-thiocyanato-1H-pyrazoles

作     者：Wei-Bao He Sai-Jie Zhao Jing-Yang Chen Jun Jiang Xiang Chen Xinhua Xu Wei-Min He Wei-Bao He;Sai-Jie Zhao;Jing-Yang Chen;Jun Jiang;Xiang Chen;Xinhua Xu;Wei-Min He

作者机构：College of Chemistry and Chemical EngineeringHunan UniversityChangsha 410082China School of Chemistry and Chemical EngineeringUniversity of South ChinaHengyang 421001China 

出 版 物：《Chinese Chemical Letters》 (中国化学快报（英文版）)

年 卷 期：2023年第34卷第2期

页      面：206-209页

核心收录：

学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学] 

基　　金：financial support from the National Natural Science Foundation of China (No. 21902014) Hunan Provincial Natural Science Foundation of China (No. 2021JJ40429) 

主　　题：Green chemistry Electrochemistry Cascade reaction Multicomponent reaction Thiocyanato 

摘      要：A practical synthetic method for 4-thiocyanato-1H-pyrazoles through the electrochemical cascade reaction of hydrazines, 1,3-diones and NH4SCN under metal-, chemical oxidant-and external electrolyte-free conditions was established. Importantly, both a gram-scale synthesis of 4-thiocyanato-1H-pyrazoles and five one-pot sequential transformations starting from hydrazine were successfully accomplished.