Fecal microbiota transplantation as potential first-line treatment for patients with Clostridioides difficile infection and prior appendectomy

作     者：Jing-Wen Zhao Bing Chang Li-Xuan Sang 

作者机构：Department of GastroenterologyShengjing Hospital of China Medical UniversityShenyang 110022Liaoning ProvinceChina Department of GastroenterologyThe First Affiliated Hospital of China Medical UniversityShenyang 110001Liaoning ProvinceChina 

出 版 物：《World Journal of Gastrointestinal Surgery》 (世界胃肠外科杂志（英文版）（电子版）)

年 卷 期：2023年第15卷第2期

页      面：303-306页

核心收录：

学科分类：1002[医学-临床医学] 10[医学] 

主　　题：Clostridioides difficile infection Appendectomy Fecal microbiota transplantation Intestinal microbiota Toxic megacolon Colectomy 

摘      要：Clostridioides difficile infection(CDI)is a global health problem.The association of appendectomy on the severity and prognosis of CDI has been reported in many literatures,but there are still contradictions.In a retrospective study entitled“Patients with Closterium diffuse infection and prior appendectomy may be prone to word outcomespublished in World J Gastrointest Surg 2021,the author found that prior appendectomy affects the severity of CDI.Appendectomy may be a risk factor for increasing the severity of CDI.Therefore,it is necessary to seek alternative treatment for patients with prior appendectomy when they are more likely to have severe or fulminant CDI.