Cistanche Deserticola for Regulation of Bone Metabolism:Therapeutic Potential and Molecular Mechanisms on Postmenopausal Osteoporosis

作     者：WANG Cheng LI Feng LI Yang FENG Hui ZHAO Min-wei TU Peng-fei TIAN Hua WANG Cheng;LI Feng;LI Yang;FENG Hui;ZHAO Min-wei;TU Peng-fei;TIAN Hua

作者机构：Department of Orthopaedics/Engineering Research Center of Bone and Joint Precision Medicine/Beijing Key Laboratory of Spinal Disease ResearchPeking University Third HospitalBeijing100191China Peking University School of Pharmaceutical SciencesBeijing100191China 

出 版 物：《Chinese Journal of Integrative Medicine》 (中国结合医学杂志（英文版）)

年 卷 期：2023年第29卷第1期

页      面：74-80页

核心收录：

学科分类：100506[医学-中医内科学] 1006[医学-中西医结合] 1005[医学-中医学] 1002[医学-临床医学] 10[医学] 100602[医学-中西医结合临床] 

基　　金：Supported by Key Clinical Projects of Peking University Third Hospital(No.BYSYZD2019037) National Natural Science Foundation of China(No.82001481) 

主　　题：osteoporosis Cistanche deserticola bone metabolism Chinese medicine 

摘      要：Osteoporosis is a generalized disease of bone that leads to a loss of bone density and bone mass,destruction of bone microstructure,increased brittleness and therefore *** present,the main treatment of Western medicine is drug therapy such as bisphosphonates,calcitriol,vitamin D,***,long-term use of these drugs may bring some adverse *** herbal medicine Cistanche deserticola could regulate bone metabolism by promoting osteoblast activity and inhibiting osteoclast activity with low toxicity and adverse ***,Cistanche deserticola has attracted increasing attention for its efficacy in the prevention and treatment of osteoporosis in recent *** we present a literature review of the molecular pathways involved in osteoporosis and the effects of Cistanche deserticola on bone *** objective is to clarify the mechanism of Cistanche deserticola in the treatment of osteoporosis.