Liver dysfunction-related COVID-19:A narrative review
作者机构：Department of BiochemistryUniversity of Anbar College of MedicineRamadi City 31001AnbarIraq Department of Surgery/OtolaryngologyUniversity of Anbar College of MedicineRamadi City 31001AnbarIraq
出 版 物：《World Journal of Meta-Analysis》 (世界荟萃分析杂志)
年 卷 期：2023年第11卷第1期
页 面：5-17页
学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学]
主 题：Liver dysfunction Liver function test SARS-CoV-2 Mortality Critical illness COVID-19
摘 要：The coronavirus 2019 disease(COVID-19)is caused by a novel coronavirus,severe acute respiratory syndrome coronavirus *** disease was designated by the World Health Organization as a pandemic on March 11,2020,which is not seen *** are no classical features among the cases of the disease owing to the involvement of nearly all body tissues by the *** involvement is one of the characteristics of the COVID-19 *** are six possible mechanisms of such involvement:Direct virus injury,drug-induced effect,inflammatory cytokine storm,hypoxia-ischemic destruction,abnormalities in liver function tests,and pre-existing chronic liver *** abnormalities are seen commonly in the severe or critical stage of ***,these abnormalities determine the COVID-19 severity and carry a high rate of morbidity and *** elderly and patients with comorbidities like diabetes mellitus and hypertension are more vulnerable to liver *** issue that needs to be disclosed is the liver manifestations following the COVID-19 vaccination,such as autoimmune *** note,complete vaccination with third and fourth booster doses is necessary for patients with previous chronic liver diseases or those who have been subjected to liver *** review aims to explore the various aspects of liver dysfunction during the COVID-19 course regarding the epidemiological features,predisposing factors,pathophysiological mechanisms,hepatic manifestations due to COVID-19 or following vaccination,role of liver function tests in the assessment of COVID-19 severity,adverse effects of the therapeutic agents for the disease,and prognosis.
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