Eu^(3+)-doped Bovine Serum Albumin-derived Carbon Dots for Ratiometric Fluorescent Detection of Tetracycline

作     者：Tian-Tian Zhang Zi-Han Chen Guo-Yue Shi Min Zhang Tian-Tian Zhang;Zi-Han Chen;Guo-Yue Shi;Min Zhang

作者机构：School of Chemistry and Molecular EngineeringShanghai Key Lab for Urban Ecological Processes and Eco-RestorationEast China Normal UniversityShanghai200241China 

出 版 物：《Journal of Analysis and Testing》 (分析检测（英文）)

年 卷 期：2022年第6卷第4期

页      面：365-373页

核心收录：

学科分类：0710[理学-生物学] 1002[医学-临床医学] 07[理学] 1001[医学-基础医学(可授医学、理学学位)] 070302[理学-分析化学] 0703[理学-化学] 

基　　金：supported by the fund of the Shanghai Science and Technology Committee (19ZR1473300) the director fund of Shanghai Key Lab for Urban Ecological Processes and Eco-Restoration (SHUES2022C03) the Fundamental Research Funds for the Central Universities 

主　　题：carbon dots Europium ion Ratiometric fluorescence Tetracycline 

摘      要：The abuse of antibiotics has become a global concern,thus it is significant to develop simple antibiotic assays.Herein,a novel type of lanthanide-doped bovine serum albumin(BSA)derived carbon dots(BCDs)dubbed Eu-BCDs has been unveiled for ratiometric fluorescent detection of tetracycline(TC),which was formed from the one-step hydrothermal reaction of Eu^(3+)and BSA.Upon challenge with TC,the blue fluorescence of Eu-BCDs at 448 nm was gradually quenched due to the internal filtration effect,while the characteristic red fluorescence of Eu^(3+)at 618 nm was significantly enhanced owning to the antenna effect,leading to the ratiometric fluorescent detection of TC with fast response(2 min),a wide linear dynamic range(0-80μmol/L),and high selectivity and sensitivity(limit of detection(LOD)of 3 nmol/L).Moreover,Eu-BCDs can be successfully applied for the ratiometric fluorescent detection of TC in environmental and biological samples,such as river water,milk,honey and serum.The Eu-BCDs sensing platform would have great application potential in view of its simple preparation,rapid response,high sensitivity and good selectivity.