Comparison of short-term toxicity of 14 common phycotoxins(alone and in combination)to the survival of brine shrimp Artemia salina

作     者：Yuting Zhang Shanshan Song Bin Zhang Yang Zhang Miao Tian Ziyi Wu Huorong Chen Guangmao Ding Renyan Liu Jingli Mu Yuting Zhang;Shanshan Song;Bin Zhang;Yang Zhang;Miao Tian;Ziyi Wu;Huorong Chen;Guangmao Ding;Renyan Liu;Jingli Mu

作者机构：Institute of OceanographyCollege of Geography and OceanographyMinjiang UniversityFuzhou350108China Fuzhou Institute of OceanographyFuzhou350108China Department of Marine ChemistryNational Marine Environmental Monitoring CenterDalian116023China Fujian Marine Environment and Fishery Resource Monitoring CenterFuzhou350003China 

出 版 物：《Acta Oceanologica Sinica》 (海洋学报（英文版）)

年 卷 期：2023年第42卷第2期

页      面：134-141页

核心收录：

学科分类：083002[工学-环境工程] 0830[工学-环境科学与工程（可授工学、理学、农学学位）] 07[理学] 08[工学] 09[农学] 0903[农学-农业资源与环境] 0713[理学-生态学] 

基　　金：The National Natural Science Foundation of China under contract No.41576120 the Special Fund Project for Marine and Fishery Protection and Development in Fujian Province,China under contract No.FZJZ-2021-1 the National Key R&D Program of China under contract No.2017YFC1404803 

主　　题：LC_(50) harmful algal blooms binary exposure ecological risk 

摘      要：Toxic harmful algal blooms(HABs)can cause deleterious effects in marine organisms,threatening the stability of marine *** is well known that different strains,natural populations and growth conditions of the same toxic algal species may lead to different amount of phycotoxin production and the ensuing *** fully assess the ecological risk of toxic HABs,it is of great importance to investigate the toxic effects of phycotoxins in marine *** this study,the short-term toxicity of 14 common phycotoxins(alone and in combination)in the marine zooplankton Artemia salina was *** 48 h LC_(50)of the 14 phycotoxins varied from 0.0193µg/mL to 2.415µg/*** most potent phycotoxin was azaspiracids-3(AZA3;with a LC_(50)of 0.0193µg/mL),followed by azaspiracids-2(AZA2;0.0226µg/mL),pectenotoxin-2(PTX2;0.0460µg/mL)and dinophysistoxin-1(DTX1;0.0818µg/mL).For the binary exposure,okadaic acid(OA)induced potential additive effects with DTX1,probably due to their similar structure(polyether fatty acid)and mode of action(attacking the serine/threonine phosphoprotein phosphatases).On the other hand,OA showed potential antagonistic effects with PTX2,which might be accounted for by their activation on the detoxification activity of cytochrome P450 *** addition,DTX1 induced potential synergetic effects with saxitoxin(STX),yessotoxin(YTX)or PTX2,suggesting the hazard potency of the mixtures of DTX1 and other phycotoxins(like STX,YTX and PTX2)with regard to the ecological *** results provide valuable toxicological data for assessing the impact of phycotoxins on marine planktonic species and highlight the potential ecological risk of toxic HABs in marine ecosystems.