Chest computed tomography findings of the Omicron variants of SARS-CoV-2 with different cycle threshold values
作者机构：Department of RadiologyShanghai Xuhui Dahua HospitalShanghai 200237China Department of Clinical LaboratoryShanghai Xuhui Dahua HospitalShanghai 200237China
出 版 物：《World Journal of Clinical Cases》 (世界临床病例杂志)
年 卷 期：2023年第11卷第4期
页 面：756-763页
核心收录：
学科分类：1002[医学-临床医学] 100202[医学-儿科学] 10[医学]
主 题：COVID-19 SARS-CoV-2 Omicron variant Computed tomography Cycle threshold Polymerase chain reaction
摘 要：BACKGROUND The Omicron variant of severe acute respiratory syndrome coronavirus 2(SARSCoV-2)mainly infects the upper respiratory *** study aimed to determine whether the probability of pulmonary infection and the cycle threshold(Ct)measured using the fluorescent polymerase chain reaction(PCR)method were related to pulmonary infections diagnosed via computed tomography(CT).AIM To analyze the chest CT signs of SARS-CoV-2 Omicron variant infections with different Ct values,as determined via *** The chest CT images and PCR Ct values of 331 patients with SARS-CoV-2Omicron variant infections were retrospectively collected and categorized into low(25),medium(25.00-34.99),and high(≥35)Ct *** characteristics of chest CT images in each group were statistically *** The PCR Ct values ranged from 13.36 to 39.81,with 99 patients in the low,155 in the medium,and 77 in the high Ct *** abnormal chest CT signs were detected,namely,focal infection,patchy consolidation shadows,patchy groundglass shadows,mixed consolidation ground-glass shadows,subpleural interstitial changes,and pleural *** infections were less frequent in the low Ct group than in the medium and high Ct groups;these infections were the most common sign in the medium and high Ct *** consolidation shadows and pleural changes were more frequent in the low Ct group than in the other two *** number of patients with two or more signs was greater in the low Ct group than in the medium and high Ct *** The chest CT signs of patients with pulmonary infection caused by the Omicron variants of SARSCoV-2 varied depending on the Ct *** of the characteristics of Omicron variant infection can help subsequent planning of clinical treatment.
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