Multi-faceted small molecule for Alzheimer’s disease

作     者：Min Hee Park Hee Kyung Jin Jae-sung Bae Min Hee Park;Hee Kyung Jin;Jae-sung Bae

作者机构：KNU Alzheimer’s Disease Research InstituteDepartment of PhysiologySchool of MedicineKyungpook National UniversityDaeguSouth Korea KNU Alzheimer’s Disease Research InstituteDepartment of Laboratory Animal MedicineCollege of Veterinary MedicineKyungpook National UniversityDaeguSouth Korea 

出 版 物：《Neural Regeneration Research》 (中国神经再生研究（英文版）)

年 卷 期：2023年第18卷第10期

页      面：2198-2199页

核心收录：

学科分类：1002[医学-临床医学] 100203[医学-老年医学] 10[医学] 

基　　金：supported by the National Research Foundation of Korea(NRF)grant funded by theKorea government(MSIT)2018M3C7A10565132020R1A2C3006734(to HKJ),2020R1A2C3006875(to JSB) supported by a grant of the Korea Health Technology R&D Project through the Korea Health Industry Development Institute(KHIDI) funded by the Ministry of Health&Welfare and MSIT,Republic of Korea(HU20C0345)(to JSB) 

主　　题：Alzheimer tau amyloid 

摘      要：The main pathologies of Alzheimer’s disease(AD)are the accumulation of amyloid-B(AB)and tau ta ngles,and these two fundamental pathologies accompany the va rious neuropathological features,such as neuroinfla mmation,loss of syna pse and neurogenesis,disruption of the blood-brain barrier(BBB),autophagy dysfunction。