Regulating the microenvironment with nanomaterials:Potential strategies to ameliorate COVID-19

作     者：Zhicheng Liu Zhuolei Han Xin Jin Jusung An Jaewon Kim Wenting Chen Jong Seung Kim Ji Zheng Jun Deng Zhicheng Liu;Zhuolei Han;Xin Jin;Jusung An;Jaewon Kim;Wenting Chen;Jong Seung Kim;Ji Zheng;Jun Deng

作者机构：Department of UrologyXinqiao HospitalThird Military Medical University(Army Medical University)Chongqing 400037China Department of UrologyUrological Surgery Research InstituteSouthwest HospitalThird Military Medical University(Army Medical University)Chongqing 400038China Institute of Burn ResearchSouthwest HospitalState Key Lab of TraumaBurn and Combined InjuryChongqing Key Laboratory for Disease ProteomicsThird Military Medical University(Army Medical University)Chongqing 400038China Tianjin Key Laboratory of Composite and Functional MaterialsSchool of Materials Science and EngineeringTianjin UniversityTianjin 300350China Department of ChemistryKorea UniversitySeoul 02841South Korea Department of Rheumatology and Clinical ImmunologyArmy Medical CenterThird Military Medical University(Army Medical University)Chongqing 400042China 

出 版 物：《药学学报:英文版》 (Acta Pharmaceutica Sinica B)

年 卷 期：2023年第13卷第9期

页      面：3638-3658页

核心收录：

学科分类：1007[医学-药学(可授医学、理学学位)] 1004[医学-公共卫生与预防医学(可授医学、理学学位)] 100401[医学-流行病与卫生统计学] 10[医学] 

基　　金：financially supported by the National Natural Science Foundation of China(No.92168106,China) the key project for clinical innovation of Third Military Medical University(No.CX2019LC107,China) the National Research Foundation of Korea(CRI project No.2018R1A3B1052702,Korea) 

主　　题：Coronavirus disease 19 Severe acute respiratory syndrome coronavirus 2 Therapeutic approaches Nanotechnology Nanomaterial technologies Microenvironment Microenvironmental disorder Altered homeostasis 

摘      要：COVID-19,caused by SARS-CoV-2,has resulted in serious economic and health *** treatments remain inadequate to extinguish the epidemic,and efficient therapeutic approaches for COVID-19 are urgently being ***,accumulating evidence suggests that microenvironmental disorder plays an important role in the progression of COVID-19 in *** addition,recent advances in nanomaterial technologies provide promising opportunities for alleviating the altered homeostasis induced by a viral infection,providing new insight into COVID-19 *** literature reviews focus only on certain aspects of microenvironment alterations and fail to provide a comprehensive overview of the changes in homeostasis in COVID-19 *** fill this gap,this review systematically discusses alterations of homeostasis in COVID-19 patients and potential ***,advances in nanotechnology-based strategies for promoting homeostasis restoration are ***,we discuss the challenges and prospects of using nanomaterials for COVID-19 *** review provides a new strategy and insights into treating COVID-19 and other diseases associated with microenvironment disorders.