Clinical and molecular features of human cystic echinococcosis in Tehran,Iran,2011-2019
作者机构：Parasitology&Entomology DepartmentFaculty of Medical SciencesTarbiat Modares UniversityTehranIran
出 版 物：《Asian Pacific Journal of Tropical Medicine》 (亚太热带医药杂志（英文版）)
年 卷 期：2022年第15卷第12期
页 面：558-567页
核心收录：
学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学]
基 金：Tarbiat Modares University TMU
主 题：Human cystic echinococcosis Clinical features Genotype Tehran
摘 要：Objective:To evaluate the clinical and molecular features of human cystic echinococcosis in Tehran,***:In this cross-sectional study,all human cystic echinococcosis patients admitted to Tehran’s hospitals from 2011 to 2019 were enrolled,and demographic characteristics,clinical findings,and laboratory data were ***,paraffin-embedded and fresh tissue samples of 175 cystic echinococcosis patients were evaluated for molecular *** samples’isolated DNA was used to amplify cytochrome c oxidaseⅠand NADH dehydrogenase subunitⅠ***,the morphological features of fresh samples were ***:In total,175 patients with a mean age of 45(9-98)years were admitted to Tehran’s hospitals diagnosed with cystic ***,the highest(26.9%)and the lowest(2.9%)prevalence of cystic echinococcosis cases were in the 16-30 and 1-15 years range,***/female ratio was 0.96(49.1%vs.50.9%).The liver was affected in 92 patients(52.6%),and two or more organs were infected in 7 patients(4.0%).The cysts’diameter varied from 1 to 25 cm,and 96.0%of the patients had a single hydatid *** patients underwent radical surgery and the PAIR technique was applied for all *** significant difference was observed between the protoscolex hooks of pulmonary and hepatic cysts.G1-G3 had the highest percentage(99.4%)over other identified G6 genotypes(0.6%).Conclusions:The sheep-dog cycle plays an important role in transmitting the human cystic echinococcosis infection in Tehran.
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