Additive manufacturing of multi-morphology graded titanium scaffolds for bone implant applications
作者机构：Shunde Graduate School of University of Science and Technology BeijingFoshan 528399China National Engineering Research Center for Advanced Rolling and Intelligent ManufacturingInstitute of Engineering TechnologyUniversity of Science and Technology BeijingBeijing 100083China Beijing Advanced Innovation Center for Materials Genome EngineeringState Key Laboratory for Advanced Metals and MaterialsUniversity of Science and Technology BeijingBeijing 100083China National Engineering Technology Research Center of Flat Rolling EquipmentInstitute of Engineering TechnologyUniversity of Science and Technology BeijingBeijing 100083China Bristol Dental SchoolUniversity of BristolBristol BS12LYUK
出 版 物：《Journal of Materials Science & Technology》 (材料科学技术（英文版）)
年 卷 期：2023年第139卷第8期
页 面：47-58页
核心收录：
学科分类：08[工学] 080501[工学-材料物理与化学] 0805[工学-材料科学与工程（可授工学、理学学位）]
基 金：This work was financially supported by the National Natural Science Foundation of China(Nos.51922004 and 51874037) the State Key Lab of Advanced Metals and Materials,University of Sci-ence and Technology Beijing(Nos.2020Z-04,2021Z-03,and 2022Z-12) the Fundamental Research Funds for the Central Universi-ties(Nos.FRF-TP-19005C1Z and 06500236) the Interdisciplinary Research Project for Young Teachers of USTB(Fundamental Re-search Funds for the Central Universities,No.FRF-IDRY-20-023) the Postdoctor Research Foundation of Shunde Graduate School of University of Science and Technology Beijing(No.2022BH001) the China Postdoctoral Science Foundation(No.2021M700377) the Guangdong Basic and Applied Basic Research Foundation(No.2021A1515110548) the State Key Laboratory of Powder Metallurgy,Central South University and the Beijing Natural Science Founda-tion(No.2212035)
主 题：Bone implants Multi-morphology graded titanium scaffolds Finite element analysis Selective laser melting Cytocompatibility
摘 要：Porous Titanium scaffolds have attracted widespread attention as bone implants for avoiding the stress shielding effect and promoting *** this study,multi-morphology graded scaffolds hy-bridized by Primitive and Gyroid structures with porosity of 50,60,and 70%were designed(denoted as PG50,PG60,and PG70,respectively)and fabricated by selective laser *** simulation results showed that the maximum von-Mises stress of hybridized scaffolds increased from 504.22 to 884.24 MPa with *** permeability and average pore size of multi-morphology PG50,PG60,and PG70 were in the range of 3.58×10^(-9)-5.50×10^(-9) m^(2) and 568.1-758.4μm,*** microstructure of multi-morphology graded scaffolds consisted of a fully martensiticα′*** permeabilities of PG50 and PG60 were 3.27×10^(-9) and 4.35×10^(-9) m^(2),respectively,which were within the range of human bone(0.01-12.1×10^(-9) m^(2)).Elastic modulus and compressive yield strength of PG50 and PG60 ranged within 5.93^(-9).86 and 180.06-257.08 MPa,***,the PG50 not only exhibited a similar elastic modulus compared to human cortical bone(10.1 GPa)but also had higher strength(257.08 vs 131 MPa).The results of in vitro biocompatibility assay showed that PG50 and PG60 have better cyto-compatibility than mono-morphology scaffolds with the same *** together,PG50 is promising to be used for the restoration of bone defects due to its excellent mechanical properties,appropriate per-meability,and good cytocompatibility.
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