Single-atom nanozymes towards central nervous system diseases

作     者：Weichen Wei Weichen Wei

作者机构：Department of NanoengineeringUniversity of California San DiegoLa Jolla 92093USA 

出 版 物：《Nano Research》 (纳米研究（英文版）)

年 卷 期：2023年第16卷第4期

页      面：5121-5139页

核心收录：

学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学] 

基　　金：supported by Jacobs Fellowship from the University of California San Diego 

主　　题：single-atom nanozymes single-atom catalysis central nervous system diseases enzyme-like catalysts reactive oxygen species 

摘      要：Nanozymes have a similar catalytic mechanism to natural enzymes,with excellent performance,facile synthesis,and better ***-atom nanozymes are developed based on single-atom catalysts due to their advantages in coordination structure and electronic configuration,making them highly enzymatic-like biomimetic *** nervous system(CNS)diseases have become one of the biggest killers of human health because they are difficult to diagnose and treat,expensive,and result in serious ***-atom nanozymes have been widely used for biomedical applications,especially in oxidative-stressinduced diseases and most CNS diseases which are closely related to oxidative ***,single-atom nanozymes show promising application prospects for the treatment of CNS *** addition,due to the outstanding material properties and sensitivity of single-atom nanozymes,they also exhibit great advantages in detecting various CNS disease markers for diagnosis.