Near-infrared emissive AIE nanoparticles for biomedical applications:From the perspective of different nanocarriers
作者机构：Center for AIE ResearchShenzhen Key Laboratory of Polymer Science and TechnologyGuangdong Research Center for Interfacial Engineering of Functional MaterialsCollege of Materials Science and EngineeringShenzhen UniversityShenzhen518060GuangdongChina School of Science and EngineeringShenzhen Institute of Aggregate Science and TechnologyThe Chinese University of Hong KongShenzhen518172GuangdongChina
出 版 物：《Particuology》 (颗粒学报（英文版）)
年 卷 期：2023年第74卷第3期
页 面：103-118页
核心收录：
学科分类：081704[工学-应用化学] 07[理学] 0817[工学-化学工程与技术] 08[工学] 0805[工学-材料科学与工程（可授工学、理学学位）] 070303[理学-有机化学] 0703[理学-化学] 0702[理学-物理学]
基 金：supported by the National Natural Science Foundation of China (grant Nos.82171990,52122317,22175120) the Developmental Fund for Science and Technology of Shenzhen government (grant Nos.RCYX20200714114525101,JCYJ20190808153415062) the Natural Science Foundation for Distinguished Young Scholars of Guangdong Province (grant No.2020B1515020011) Guangdong Province Key Area R&D Program (grant No.2019B110233004).The authors acknowledge the Instrumental Analysis Center of Shenzhen University
主 题：Aggregation-induced emission Nanoparticles Biomedical applications Near-infrared emission Nanocarriers
摘 要：Fluorescent imaging based on near-infrared(NIR)fluorophores has revolutionized the techniques employed for detecting biological events in depth owing to their advantages referring to diminished photon scattering,high signal-to-noise ratio and better light transparence through *** for conventional luminogens,the nanofabrication of those innately hydrophobicπ-conjugated architectures into water-dispersible nanoparticles(NPs)may result in attenuated fluorescent intensity deriving from the detrimental distribution ofπ-πinteractions in the confined ***,chromophores possessing aggregation-induced emission(AIE)characteristics emit boosted brightness at aggregate level according to the mechanism of restriction of intramolecular motion(RIM).In this review,we summarize the recent progresses of NIR emissive AIE NPs for multifarious biomedical applications from the viewpoint of different fabricated manners,mainly covering self-assembly and matrices assisted ***,the current challenges and future research directions of NIR AIE NPs are briefly discussed.
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