A Robust Strategy for Precise Fabrication of Rigid-Flexible Coupling Dendrimers toward Self-Coordinated Hierarchical Assembly

作     者：Xing Wang Peiyuan Gao Juan Wang Yanyu Yang Yezi You Decheng Wu 

作者机构：Beijing National Laboratory for Molecular SciencesInstitute of ChemistryChinese Academy of SciencesBeijing 100190 University of Chinese Academy of SciencesBeijing 100049 College of Materials Science and EngineeringZhengzhou UniversityZhengzhou 450001 Hefei National Laboratory for Physical Sciences at the MicroscaleCAS Key Laboratory of Soft Matter ChemistryDepartment of Polymer Science and EngineeringUniversity of Science and Technology of ChinaHefei 230026 

出 版 物：《CCS Chemistry》 (中国化学会会刊（英文）)

年 卷 期：2021年第3卷第4期

页      面：1093-1104页

学科分类：07[理学] 0703[理学-化学] 

基　　金：This work was supported by NSFC(nos.51973226 21725403 51803188 and 21504096) the Ministry of Science and Technology of China(no.2014CB932200) and the China Postdoctoral Science Foundation(nos.2018M642783 and 2019T120636). 

主　　题：dendrimer POSS hierarchical selfassembly rigid-flexible coupling phase separation coordinative interaction 

摘      要：Advances in nanotechnology depend upon expanding the ability to create biologically inspired complex materials with well-defined multidimensional structures.Fabrication of hybrid hierarchical structures by combining colloidal organic and inorganic building blocks remains a challenge due to the difficulty in preparing a diverse spectrum of rigid-flexible coupling units of precise shape and size.Herewe reportageneral strategy for crafting amyriad of uniform aggregates via manipulating self-assembly of distinct dendimers with precisely controlled polyhed raloligomeric silse squioxane(POSS)-embedded cores integrating stiffness and ductility.The rigidity of POSS units exerts steric effects onself-amplification of hydrophobic do mains while the flexibility from internally ductile linkages provides ideal scenarios in establishing self-adaptive structural optimization,which subsequently drive the assemblies to proceed into hierarchical self-assembly via multiple coordination effects,generating highly complex multi compartment micelles(MCMs)without any preprocessing.Our facile approach enables a robust modular nanofabrication of well-organized dendrimers toward artificial functional systems with defined geometric architectures and intriguing functions for advanced biological applications.