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Nanopore techniques as a potent tool in the diagnosis and treatment of endophthalmitis:a literature review

作     者:Zi-Yue Li Ke-Yi-Zhi Xu Wei Jin 

作者机构:Eye CenterRenmin Hospital of Wuhan UniversityWuhan 430060Hubei ProvinceChina The Computer School of Wuhan UniversityWuhan 430072Hubei ProvinceChina 

出 版 物:《International Journal of Ophthalmology(English edition)》 (国际眼科杂志(英文版))

年 卷 期:2022年第15卷第12期

页      面:2009-2016页

核心收录:

学科分类:1002[医学-临床医学] 100212[医学-眼科学] 10[医学] 

主  题:postoperative endophthalmitis high-throughput sequencing metagenomics long-read nanopore targeted sequencing pathogen identification 

摘      要:Endophthalmitis is a serious ophthalmic disease characterized by changes in the eye s posterior segment,such as hypopyon and intraocular inflammation,vitritis being a ***-caused endophthalmitis can lead to irreversible vision loss,accompanied by eye pain or eye distention,and in the most severe cases the removal of the *** such as bacteria,fungi,viruses,and parasites typically account for the disease and the entry pathways of the microbial can be divided into either endogenous or exogenous approaches,according to the origin of the etiological *** endophthalmitis can be derived from various occasions(such as postoperative complications or trauma)while endogenous endophthalmitis results from the bloodstream which carries pathogens to the *** review aims to summarize the application of new technology in pathogen identification of endophthalmitis so as to prevent the disease and better guide clinical diagnosis and treatment.

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