Molecular bases of morphologically diffused tumors across multiple cancer types

作     者：Dingyun Liu Feiyang Xing Yueying Wang Jun Xiao Zheng An Ying Xu Dingyun Liu;Feiyang Xing;Yueying Wang;Jun Xiao;Zheng An;Ying Xu

作者机构：College of Computer Science and TechnologyJilin University Center for Cancer Systems Biology China-Japan Union Hospital of Jilin University School of Life SciencesJilin University China Computational Systems Biology Lab Department of Biochemistry and Molecular Biology and Institute of BioinformaticsUniversity of Georgia 

出 版 物：《National Science Review》 (国家科学评论(英文版))

年 卷 期：2022年第9卷第11期

页      面：65-67页

核心收录：

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

基　　金：Georgia Research Alliance 

主　　题：identification enantioselective semisynthesis (−)-anisomelic acid oral agent anti-SARS-CoV-2 

摘      要：Diffuse gastric cancer (DGC) and intestinal gastric cancer (IGC) are the two main gastric cancer subtypes [1]. Morphologically, DGC consists of numerous disjoint tiny tumors while IGC forms one or a few solid tumors (Supplementary Supplementary Fig. S1)[1,2]. In-depth studies have discovered that DGCs generally have an ill-defined or missing glandular structure and reduced cell–cell adhesion,