Natural co-infection of fowl adenovirus type E-8b and avian hepatitis E virus in parental layer breeders in Hebei,China
作者机构：China Institute of Veterinary Drug ControlBeijing100081China College of Animal Science and Veterinary MedicineShandong Agricultural UniversityTai'an City271018China
出 版 物：《Virologica Sinica》 (中国病毒学（英文版）)
年 卷 期：2023年第38卷第2期
页 面：317-320页
核心收录：
学科分类：0710[理学-生物学] 090601[农学-基础兽医学] 09[农学] 0906[农学-兽医学]
基 金：supported by the National Key Research and Development Program of China(2022YFD1800602) the Public welfare project of China Institute of Veterinary Drug Control(GY202104,202105,GY202012,and GY202008)
主 题：poultry layer representing
摘 要：Dear Editor,Fowl adenovirus(FAdV)and avian hepatitis E virus(aHEV)are the most important causative agents of hepatic injury,representing one of the greatest health concerns in layer chicken flocks(LCFs)in China and causes substantial economic *** are non-enveloped,double-stranded DNA viruses containing a genome of 43–45 kb in size and belong to the genus Aviadenovirus in the family of Adenoviridae(Hess,2000).Based on restriction enzyme digestion patterns and serum cross-neutralization tests,FAdV is currently clustered into five species(FAdV-A–FAdV-E)with 12 serotypes(FAdV-1 to-7,FAdV-8a,FAdV-8b,and FAdV-9 to-11).Different serotypes of FAdVs cause different clinical symptoms in poultry ***-1 can induce gizzard erosion in chickens,whereas inclusion body hepatitis(IBH)in chickens is often associated with FAdV-2,-8a,-8b,***-4 causes hydropericardium hepatitis syndrome and IBH in chickens,and its infections have caused severe economic losses in the global poultry industry(Ye et al.,2016).Avian hepatitis E virus(aHEV)is a major causative agent of big liver and spleen disease(BLS),hepatitis splenomegaly syndrome,and hepatic rupture hemorrhage syndrome(HRHS)in chickens(Sun et al.,2019).
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