Mechanical Force Remodeling the Adult Brain

作     者：Chen Zhang Shuai Liu Yong-Chun Yu Qingjian Han 

作者机构：State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain ScienceInstitutes of Brain ScienceFudan UniversityShanghai 200032China 

出 版 物：《Neuroscience Bulletin》 (神经科学通报（英文版）)

年 卷 期：2023年第39卷第5期

页      面：877-879页

核心收录：

学科分类：1002[医学-临床医学] 1001[医学-基础医学(可授医学、理学学位)] 10[医学] 

基　　金：AcknowledgementsThis research highlight was supported by STI 2030-Major Projects(2021ZD0203201) the National Natural Science Foundation of China(81971034 32271047) The Innovative Research Team of High-level Local Universities in Shanghai Natural Science Foundation of Shanghai(22ZR1413800) The Program for Professor of Special Appointment(Eastern Scholar)at Shanghai Institutions of Higher Learning Shanghai Municipal Science and Technology Major Project(2018SHZDZX01) ZJ Lab and Shanghai Center for Brain Science and Brain-Inspired Technology Lingang Laboratory(LGQS-202203-12) Innovation Team and Talents Cultivation Program of National Administration of Traditional Chinese Medicine(ZYYCXTDC-202008) and Shanghai Style of TCM for Inheritance and Innovation Team from Shanghai Municipal Health Commission(2021LPTD-007) Shanghai Artificial Intelligence Innovation and Development Project-Intelligent Dermatology Clinic Based on Modern TCM Diagnostic Technology No.2020-RGZN-02038. 

主　　题：vital maintenance migration 

摘      要：The interactions between neural stem cells(NSCs)and their niche are essential for their maintenance,proliferation,differentiation,and migration,which contribute to brain plasticity,learning and memory,and cognition[1].As one of the key components of the NSC niche,astrocytes are vital in regulating the processes underlying brain development such as neuro-/gliogenesis,angiogenesis,axonal outgrowth,synaptogenesis,and synaptic pruning[2].Chemical and electrical signals mediated by adhesion molecules,the extracellular matrix,paracrine secretion.