Ambient Fine Particulate Matter Exposure and Blood Pressure:Evidence from a Large Chinese Multiple Follow-Up Study

作     者：JIANGTULU Bahabaike LAN Chang Xin CHEN Jun Xi CHEN Xi WANG Bin XUE Tao JIANGTULU Bahabaike;LAN Chang Xin;CHEN Jun Xi;CHEN Xi;WANG Bin;XUE Tao

作者机构：Institute of Reproductive and Child HealthKey Laboratory of Reproductive HealthNational Health Commission of the People's Republic of ChinaBeijing 100191China Department of Epidemiology and BiostatisticsSchool of Public HealthPeking UniversityBeijing 100191China National Institute of Environmental HealthChinese Center for Disease Control and Prevention(China CDC)Beijing 102206China 

出 版 物：《Biomedical and Environmental Sciences》 (生物医学与环境科学（英文版）)

年 卷 期：2023年第36卷第1期

页      面：38-49页

核心收录：

学科分类：1004[医学-公共卫生与预防医学(可授医学、理学学位)] 100402[医学-劳动卫生与环境卫生学] 10[医学] 

主　　题：Fine particulate matter PM_(2.5) Blood pressure Risk assessment Preventive medicine 

摘      要：Objective This study aimed to investigate the association of ambient PM_(2.5)exposure with blood pressure(BP)at the population level in *** A total of 14,080 participants who had at least two valid blood pressure records were selected from the China Health and Retirement Longitudinal Survey during 2011–*** long-term PM_(2.5)exposure was assessed at the geographical level,on the basis of a regular 0.1°×0.1°grid over China.A mixed-effects regression model was used to assess *** Each decrease of 10μg/m^(3)in the 1 year-mean PM_(2.5)concentration(FPM1Y)was associated with a decrease of 1.24[95%confidence interval(CI):0.84–1.64]mmHg systolic BP(SBP)and 0.50(95%CI:0.25–0.75)mmHg diastolic BP(DBP),respectively.A robust association was observed between the long-term decrease in PM_(2.5)and decreased BP in the middle-aged and older *** a generalized additive mixed model,we further found that SBP increased nonlinearly overall with FPM1Y but in an approximately linear range when the FPM1Y concentration was70μg/m^(3);In contrast,DBP increased approximately linearly without a clear *** Efficient control of PM_(2.5)air pollution may promote vascular health in *** study provides robust scientific support for making the related air pollution control policies.