黑色人种鳞状细胞癌患者:80例(法语)

作     者：Dieng M.-T. Diop N.-N. Déme A. 刘艳 

作者机构：Serv. de Dermatol. et de Venereol. CHU le Dantec BP 3001 Dakar Senegal 

出 版 物：《世界核心医学期刊文摘（皮肤病学分册）》 (Digest of the World Core Medical JOurnals:Dermatology)

年 卷 期：2005年第1卷第4期

页      面：51-52页

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主　　题：黑色人种 鳞状细胞癌 癌前皮肤病 恶性上皮瘤 崩蚀性溃疡 烧伤瘢痕 鳞癌患者 遗传性皮肤病 着色性干皮病 医学领域 

摘      要：Introduction. Squamous cell carcinoma is a malignant epithelial tumor of the skin, rarely observed in blackskin. It often complicates an acquired or congenital pre-neoplastic dermatosis. We report on 80 cases of squamous cell carcinoma having occurred in black African patients from Senegal. Patients and methods. We retrospectively analyzed all the medical files of patients followed-up in the department for histologically confirmed squamous cell carcinoma from 1980 to 1999. Results. Eighty cases of carcinoma were collected. The mean age of the patients was of 47 years (range: 1 to 85) and the sex ratio was of 1.35 (46 men and 34 women). A pre-neoplastic dermatosis was identified in 65%of the patients. Acquired pre-neoplastic dermatosis was: heat burn scars (15 cases), chronic discoid lupus erythematosus (6 cases) and chronic phagedenic ulcer (4 cases). Pre-neoplastic genodermatoses were: albinism (6 cases), xeroderma pigmentosum (5 cases) and epidermodysplasia verruciformis (1 case). Lesions were multiple and cephalic in patients with genodermatosis. Death due to carcinoma occurred in 8 patients. Comments. This large series of squamous cell carcinoma emphasizes: the rarity of squamous cell carcinomas in black patients and the frequency of its occurrence on acquired pre-existing dermatosis. For many years phagedenic ulcers predominated. Our results show the regression of the latter and its increase on post-burn scars and chronic lupus erythematosus. Pre-neoplastic genodermatoses thatdeterminemultiplecancers,usuallylocatedonsun-exposed areas and occurring in young patients, are particularly severe.