Cell therapy for the treatment of reproductive diseases and infertility:an overview from the mechanism to the clinic alongside diagnostic methods

作     者：Kosar Babaei Mohsen Aziminezhad Seyedeh Elham Norollahi Sogand Vahidi Ali Akbar Samadani Kosar Babaei;Mohsen Aziminezhad;Seyedeh Elham Norollahi;Sogand Vahidi;Ali Akbar Samadani

作者机构：Non-Communicable Disease Research CenterNeyshabur University of Medical SciencesNeyshaburIran UMR INSERM U 1122IGE-PCVInteractions Gène-Environment En Physiopathologie Cardiovascular UniversitéDe LorraineNancyFrance Cancer Research Center and Department of ImmunologySemnan University of Medical SciencesSemnanIran Medical Biology Research CenterKermanshah University of Medical SciencesKermanshahIran Guilan Road Trauma Research CenterGuilan University of Medical SciencesRashtIran 

出 版 物：《Frontiers of Medicine》 (医学前沿（英文版）)

年 卷 期：2022年第16卷第6期

页      面：827-858页

核心收录：

学科分类：1001[医学-基础医学(可授医学、理学学位)] 100101[医学-人体解剖与组织胚胎学] 10[医学] 

主　　题：infertility stem cell therapy mesenchymal stem cells pluripotent stem cells 

摘      要：Infertility is experienced by 8%–12%of adults in their reproductive period globally and has become a prevalent *** routine therapeutic methods,stem cells are rapidly being examined as viable alternative therapies in regenerative medicine and translational *** progress has been made in understanding the biology and purpose of stem *** affected pluripotent stem cells(iPSCs)and mesenchymal stem cells(MSCs)are further studied for their possible use in reproductive medicine,particularly for infertility induced by premature ovarian insufficiency and ***,this study discusses current developments in the use of some kinds of MSCs such as adipose-derived stem cells,bone marrow stromal cells,umbilical cord MSCs,and menstrual blood *** methods have been used to manage ovarian and uterine disorders,and each technique presents a novel method for the therapy of infertility.