The beneficial effects of Tartary buckwheat (Fagopyrum tataricum Gaertn.) on diet-induced obesity in mice are related to the modulation of gut microbiota composition

作     者：Yiming Zhou Haoyu Lu Shen Zhao Beibei Yan Hong Wang Xiaoli Zhou Ying Xiao Yiming Zhou;Haoyu Lu;Shen Zhao;Beibei Yan;Hong Wang;Xiaoli Zhou;Ying Xiao

作者机构：School of Perfume and Aroma TechnologyShanghai Institute of TechnologyShanghai 201418China University Think Tank of Shanghai MunicipalityInstitute of Beautiful China and Ecological CivilizationShanghai 201418China 

出 版 物：《Food Science and Human Wellness》 (食品科学与人类健康（英文）)

年 卷 期：2023年第12卷第4期

页      面：1323-1330页

核心收录：

学科分类：0832[工学-食品科学与工程（可授工学、农学学位）] 1004[医学-公共卫生与预防医学(可授医学、理学学位)] 08[工学] 083202[工学-粮食、油脂及植物蛋白工程] 

基　　金：Shanghai Natural Science Foundation(20ZR1455800) the National Science Foundation of China(31871805) Shanghai Municipal Education Commission(Plateau Discipline Construction Program)and China Agriculture Research System(CARS-08-D2) 

主　　题：Tartary buckwheat High-fat diet Biochemical parameters Gut microbiota Lipid metabolism 

摘      要：The gut is home to a large number of intestinal microbiota that play an important role in the metabolism and immune system of the host.A growing body of evidence suggests that a high-fat diet is closely associated with many metabolic disorders,including fatty liver and type 2 *** to reports,Tartary buckwheat extract has a positive effect on intestinal microbiota in *** effects of Tartary buckwheat on biochemical indexes and intestinal microflora in mice were *** buckwheat protein(FGP),Tartary buckwheat resistant starch(FGS)and Tartary buckwheat flour(FGF)alleviated organ damage in mice and lowered the atherosclerotic index(AI)in ***,principal coordinate analysis(PCoA)showed that intestinal bacterial structure of FGF were separated apparently from other *** Firmicutes/Bacteroidetes(F/B)value of the high-fat(HF)-FGF group was significantly lower than that of the HF-FGP and HF-FGS *** significantly increases the abundance of beneficial bacteria such as Bifidobacterium,while decreasing the abundance of lipopolysaccharide(LPS)-producing *** of blood lipid metabolism parameters and analysis of the intestinal microbiota suggested that FGF can be more effective than FGP and FGS to reduce the effects of a high-fat diet in mice,restoring the blood parameters to values similar of those in mice fed a low-fat *** may be used to prevent or treat blood lipid metabolism disorders and intestinal microbiota disorders in mice fed a high-fat diet.