First observation of domoic acid and its isomers in shellfish samples from Shandong Province,China

作     者：Guanchao ZHENG Haiyan WU Mengmeng GUO Jixing PENG Yuxiu ZHAI Zhijun TAN Guanchao ZHENG;Haiyan WU;Mengmeng GUO;Jixing PENG;Yuxiu ZHAI;Zhijun TAN

作者机构：Key Laboratory of Testing and Evaluation for Aquatic Product Safety and QualityMinistry of Agriculture and Rural Aff airsYellow Sea Fisheries Research InstituteChinese Academy of Fishery SciencesQingdao 266071China Pilot National Laboratory for Marine Science and Technology(Qingdao)Qingdao 266237China Collaborative Innovation Center of Seafood Deep ProcessingDalian Polytechnic UniversityDalian 116034China 

出 版 物：《Journal of Oceanology and Limnology》 (海洋湖沼学报（英文）)

年 卷 期：2022年第40卷第6期

页      面：2231-2241页

核心收录：

学科分类：0710[理学-生物学] 0908[农学-水产] 07[理学] 0707[理学-海洋科学] 0815[工学-水利工程] 0713[理学-生态学] 

基　　金：Supported by the Science&Technology Basic Resources Investigation Program of China(No.2018FY100200) the National Natural Science Foundation of China(Nos.32072329,41976110) the Central PublicInterest Scientifi c Institution Basal Research Fund,CAFS(No.2020TD71) the Earmarked Fund for CARS(CARS-49) 

主　　题：domoic acid shellfi sh liquid chromatography-tandem mass spectrometry(LC-MS/MS) Shandong Province 

摘      要：A total of 133 shellfish samples were collected in seven cities of Shandong Province,China,from May to October,*** domoic acid(DA)concentrations were determined by liquid chromatographytandem mass spectrometry(LC-MS/MS),and their distribution characteristics were *** concentration was detected high in over 1/3(36.1%)of the samples of four kinds of shellfish in all three seasons in range from 0 to 102μg/*** highest DA concentrations were 102,101,36.7,and 10.2μg/kg in Crassostrea gigas,Chlamys farreri,Mactra veneriformis,and Mytilus edulis,***,Yantai(22.0μg/kg)and Weihai(16.9μg/kg)showed relatively high concentrations of DA,whereas Rizhao and Dongying presented only 0.85-and 1.76-μg/kg DA,*** concentrations in the shellfish samples were strongly related to seasonal changes,being significantly higher in autumn and summer than that in *** DA risk exposure assessments indicate that dietary seafood consumption did not pose a health threat to general human *** addition,three isomers(isoA,isoD,isoE)and 5′-epimer DA were detected in 3.00%-15.80%of the shellfish *** study is the first to observe DA and its isomers in shellfish samples of Shandong *** results demonstrate that DA contamination is very common and should be continuously monitored.