Electrospun Textile Strategies in Tendon to Bone Junction Reconstruction

作     者：Xiaoyun Xu Yifan Si Yi Zhao Qinfei Ke Jinlian Hu 

作者机构：Department of Biomedical EngineeringCity University of Hong KongHong Kong S.A.R 999077China Shanghai Frontiers Science Center of Advanced TextilesDonghua UniversityShanghai 201620China Shanghai Institute of TechnologyShanghai 200235China 

出 版 物：《Advanced Fiber Materials》 (先进纤维材料（英文）)

年 卷 期：2023年第5卷第3期

页      面：764-790页

核心收录：

学科分类：0831[工学-生物医学工程（可授工学、理学、医学学位）] 08[工学] 0836[工学-生物工程] 

基　　金：acknowledge the financial support from the Startup Grant of CityU(“Laboratory of Wearable Materials for Healthcare”,Grant 9380116) National Natural Science Foundation of China(“Study of high performance fiber to be achieved by mimicking the hierarchical structure of spider-silk”,Grant 52073241 “Study of Multi-Responsive Shape Memory Polyurethane Nanocomposites Inspired by Natural Fibers”,Grant 51673162 “Developing Spider-Silk-Model Artificial Fibers by A Chemical Synthetic Approach”,Grant 15201719) the Contract Research(“Development of Breathable Fabrics with Nano-Electrospun Membrane”,CityU ref.:9231419) 

主　　题：Electrospun Textile Tendon to bone Tissue engineering Biomimetic 

摘      要：The repair of tendon to bone junction(TBJ)remains a tremendous challenge in tissue engineering due to the complicated structure,components,mechanical properties,and cell *** order to reconstruct the tissue and restore its functionality,biomedical scaffolds with hierarchical and gradient structures have been fabricated by various *** recent decades,electrospinning has become one of the most popular methods in fabricating TBJ scaffolds due to easy fabrication,high porosity,and ECM-like nano-scale ***,mechanical properties are the pain point of electrospun biomedical *** textile technology can be exploited to compensate for this weakness,which will be deeply discussed *** review will start with a brief introduction to the structure and function of the native TBJ tissue and a short overview of electrospinning ***,different electrospun biomedical scaffolds for TBJ repair will be summarized and ***,some advanced technologies and modification methods in fabricating functionalized electrospun TBJ scaffolds are *** the end,current challenges and solutions are being proposed,which would provide instruction for the research of electrospun textile TBJ scaffolds.