Pemafibrate,a potent selective peroxisome proliferator-activated receptorαmodulator,a promising novel treatment for ischemic retinopathy?

作     者：UCCAODeokhoLee Yohei Tomita Kazuno Negishi Toshihide Kurihara Deokho Lee;Yohei Tomita;Kazuno Negishi;Toshihide Kurihara

作者机构：Department of OphthalmologyKeio University School of MedicineShinanomachiShinjuku-kuJapan 

出 版 物：《Neural Regeneration Research》 (中国神经再生研究（英文版）)

年 卷 期：2023年第18卷第7期

页      面：1495-1496页

核心收录：

学科分类：1002[医学-临床医学] 100212[医学-眼科学] 10[医学] 

基　　金：supported by the KAKENHI Nos.15K10881 and 18K09424(to TK)and JST SPRING No.JPMJSP2123(to DL) 

主　　题：retinopathy degeneration 

摘      要：Ischemic retinopathy is a retinal disease caused by ischemic *** is a common pathologic mechanism in various retinal disorders and diseases such as age-related macular degeneration,diabetic retinopathy,glaucoma,or vascular occlusion(Osborne et al.,2004).Although various murine models have been developed to understand a series of metabolic mechanisms induced by retinal ischemia and further used to test promising therapeutics,effective treatment in ischemic retinopathy has not been clearly *** is associated with the notion that the contributing pathologic metabolic pathways might be enormously complex.