Artificial liver support molecular adsorbents recirculating system therapy as a bridge to re-transplantation in two cases of long anhepatic duration

作     者：Yi-He Liu, Yu Wang, Li-Xin Yu, Li-Ying Sun, Bao-Lan Feng, Zhong-Yang Shen and Min-Min Wang Tianjin, ChinaTianjin Organ Transplantation Institute, Tianjin First Central Hospital, Tianjin 300192 , China Therapeutic Blood Purification Research Cen- ter , University of Rostock, Germany 

作者机构：Tianjin Organ Transplantation Institute Tianjin First Central Hospital Tianjin 300192 China. 

出 版 物：《Hepatobiliary & Pancreatic Diseases International》 (国际肝胆胰疾病杂志（英文版）)

年 卷 期：2004年第3卷第2期

页      面：316-317页

学科分类：1002[医学-临床医学] 100210[医学-外科学(含：普外、骨外、泌尿外、胸心外、神外、整形、烧伤、野战外)] 10[医学] 

主　　题：artificial liver support liver transplantation anhepatic molecular adsorbents recirculating system 

摘      要：BACKGROUND: Molecular adsorbents recirculating sys- tem (MARS) liver support therapy is the development of albumin dialysis. This study was to assess the successful ap- plication of MARS artificial liver support therapy as a bridge to re-transplantation in two cases of long anhepatic duration. METHODS: MARS therapy was given after failure plasma- exchange ( PE) treatment, which resulted in circulatory de- rangement and acute renal dysfunction in a 36-year-old male patient. Finally his uncontrolled anhepatic condition led to a successful re-transplantation. In another 48-year- old man who was diagnosed as having primary nonfunction (PNF) during the liver transplantation, 10-hour MARS treatment contributed to smooth bridging of his anhepatic phase. RESULTS: The two anhepatic patients were bridged for 26 and 17 hours respectively to re-transplantation with MARS therapy. CONCLUSION: Our experience proves that MARS artifi- cial liver can be an effective support for long time bridging PNF until re-transplantation is available.