What is responsible for acute myocardial infarction in combination with aplastic anemia? A case report and literature review

作     者：Ya-Nan Zhao Wei-Wei Chen Xiao-Yu Yan Kun Liu Guo-Hui Liu Ping Yang 

作者机构：Department of CardiologyChina-Japan Union Hospital of Jilin UniversityChangchun 130000Jilin ProvinceChina Department of CardiologyJilin Provincial Cardiovascular Research InstituteChangchun 130000Jilin ProvinceChina Department of CardiologyJilin Provincial Engineering Laboratory for Endothelial Function and Genetic Diagnosis of Cardiovascular DiseaseChangchun 130000Jilin ProvinceChina 

出 版 物：《World Journal of Clinical Cases》 (世界临床病例杂志)

年 卷 期：2022年第10卷第32期

页      面：11955-11966页

核心收录：

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

基　　金：Supported by the project from Provincial Science and Technology Department No.2019SC0012 

主　　题：Aplastic anemia Myocardial infarction Cyclosporine A Stanozolol Percutaneous coronary intervention Case report 

摘      要：BACKGROUND Aplastic anemia(AA)complicated with myocardial infarction(MI)is rare and associated with poor ***,we present a case of AA with recurrent acute MI(AMI)in a patient treated with cyclosporine A(CsA)and *** this patient,we suspect the long-term use of medication linked to platelets *** SUMMARY In 2017,a 45-year-old man was rushed to the emergency department of China-Japan Union Hospital due to precordial pain for 5 *** on his symptoms,medical history,blood tests,and findings from coronary angiography(CAG),the patient was diagnosed with acute anterior wall,ST-segment elevated MI,Killip II grade,AA,and *** 2021,the patient was readmitted to the hospital for 2 h due to chest *** the patient’s platelet count was 30×109/L and he had severe thrombocytopenia,we performed CAG following platelet *** coherence tomography revealed lipid plaque and thrombus mass in his right coronary *** antithrombotic approach was adjusted to employ only anticoagulants(factor Xa inhibitors)and adenosine diphosphate inhibitors(clopidogrel)after assessing the risk of bleeding/thrombotic ***-term follow-up revealed that the patient had made a good *** Patients with AA should be closely monitored for the risk of thrombosis and cardiovascularevents, particularly when taking stanozolol or CsA for an extended period of time.