Diabetes and skin cancers: Risk factors, molecular mechanisms and impact on prognosis

作     者：Elena-Codruta Dobrică Madalina Laura Banciu Vincent Kipkorir Mohammad Amin Khazeei Tabari Madeleine Jemima Cox L V Simhachalam Kutikuppala Mihnea-Alexandru Găman 

作者机构：Doctoral SchoolUniversity of Medicine and Pharmacy of CraiovaCraiova 200349Romania Department of Dermatology"Elias"University Emergency HospitalBucharest 011461Romania Department of Human AnatomyUniversity of NairobiCollege of Health SciencesNairobi 00100Kenya USERN OfficeMazandaran University of Medical SciencesSari 48175-866Iran University of New South WalesUniversity of New South WalesSydney 2052Australia Dr NTR University of Health SciencesVijayawadaAndhra Pradesh 520008India Faculty of Medicine"Carol Davila"University of Medicine and PharmacyBucharest 050474Romania 

出 版 物：《World Journal of Clinical Cases》 (世界临床病例杂志)

年 卷 期：2022年第10卷第31期

页      面：11214-11225页

核心收录：

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主　　题：Diabetes Skin cancers Squamous cell carcinoma Melanoma Basocellular carcicoma 

摘      要：Diabetes and skin cancers have emerged as threats to public health ***,their association has been less intensively *** this narrative review,we explore the common risk factors,molecular mechanisms,and prognosis of the association between cutaneous malignancies and ***,oxidative stress,low-grade chronic inflammation,genetic,lifestyle,and environmental factors partially explain the crosstalk between skin cancers and this metabolic *** addition,diabetes and its related complications may interfere with the appropriate management of cutaneous *** medication seems to exert an antineoplastic effect,however,future large,observation studies with a prospective design are needed to clarify its impact on the risk of malignancy in *** for diabetes in skin cancers,as well as close follow-up for the development of cutaneous malignancies in subjects suffering from diabetes,is warranted.