Postoperative complications and critical care management after cytoreduction surgery and hyperthermic intraperitoneal chemotherapy: A systematic review of the literature
作者机构：Department of AnaesthesiologyCritical Care and PainTata Memorial HospitalHomi Bhabha National InstituteMumbai 400012MaharashtraIndia
出 版 物：《World Journal of Critical Care Medicine》 (世界重症医学杂志)
年 卷 期：2022年第11卷第6期
页 面：375-386页
学科分类：1011[医学-护理学（可授医学、理学学位）] 10[医学]
主 题：Intensive care units Hyperthermic intraperitoneal chemotherapy Morbidity Peritoneal neoplasms Postoperative period
摘 要：BACKGROUND Cytoreductive surgery(CRS)and hyperthermic intraperitoneal chemotherapy(HIPEC)is a comprehensive treatment option performed for peritoneal surface *** almost all patients are transferred to the intensive care unit *** To describe the common and rare postoperative complications,postoperative mortality and their critical care management after *** The authors assessed 54 articles for *** text assessment identified 14 original articles regarding postoperative complications and critical care management for inclusion into the final review *** There is an exaggerated metabolic and inflammatory response after surgery which may be termed as physiological in view of the nature of surgery combined with the use of heated intraperitoneal chemotherapy with/out early postoperative intravenous *** expected postoperative course is further ***-HIPEC is a complex procedure with some life-threatening complications in the immediate postoperative period,reported morbidity rates between 12%-60%and a mortality rate of 0.9%-5.8%.Over the years,since its inception in the 1980s,postoperative morbidity and survival have significantly *** commonest postoperative surgical complications and systemic toxicity due to chemotherapy as reported in the last decade are *** CRS-HIPEC is associated with a varying rate of postoperative complications including postoperative deaths and needs early suspicion and intensive care monitoring.
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