Cow’s milk-induced gastrointestinal disorders:From infancy to adulthood

作     者：Mohammed Al-Beltagi Nermin Kamal Saeed Adel Salah Bediwy Reem Elbeltagi 

作者机构：Department of PediatricsFaculty of MedicineTanta UniversityTanta 31511AlgharbiaEgypt Department of PediatricsUniversity Medical CenterArabian Gulf UniversityManama 26671Bahrain Department of PathologyMicrobiology SectionSalmaniya Medical ComplexManama 26671Bahrain Department of PathologyMicrobiology SectionRoyal College of Surgeons in Ireland-BahrainBusaiteen 15503MuharraqBahrain Department of Chest DiseasesFaculty of MedicineTanta UniversityTanta 31527AlgharbiaEgypt Department of Chest DiseasesUniversity Medical CenterArabian Gulf UniversityManama 26671Bahrain Department of MedicineThe Royal College of Surgeons in Ireland-BahrainBusiateen 15503MuharraqBahrain 

出 版 物：《World Journal of Clinical Pediatrics》 (世界临床儿科杂志)

年 卷 期：2022年第11卷第6期

页      面：437-454页

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主　　题：Cow’s milk Adults Children Functional gastrointestinal disorders Cow’s milk protein allergy Lactose intolerance,Inflammatory bowel disease Zoonosis 

摘      要：Milk is related to many gastrointestinal disorders from the cradle to the grave due to the many milk ingredients that can trigger gastrointestinal discomfort and ***’s milk protein allergy(CMPA)is the most common food allergy,especially in infancy and childhood,which may persist into *** are three main types of CMPA;immunoglobulin E(IgE)-mediated CMPA,non-IgEmediated CMPA,and mixed *** appears before the first birthday in almost all *** may start even during the neonatal period and can be severe enough to simulate neonatal ***(often non-IgE mediated)can present with symptoms of gastroesophageal reflux,eosinophilic esophagitis,hemorrhagic gastritis,food protein-induced protein-losing enteropathy,and food protein-induced enterocolitis *** CMPAs are benign and outgrown during *** is not as common in adults as in children,but when present,it is usually severe with a protracted *** intolerance is a prevalent condition characterized by the development of many symptoms related to the consumption of foods containing *** intolerance has four typical types:Developmental,congenital,primary,and *** intolerance and CMPA may be the underlying pathophysiologic mechanisms for many functional gastrointestinal disorders in children and *** are also common in inflammatory bowel *** consumption may have preventive or promoter effects on cancer *** may also become a source of microbial infection in humans,causing a wide array of diseases,and may help increase the prevalence of antimicrobial *** editorial summarizes the common milk-related disorders and their symptoms from childhood to adulthood.