Effect of small bowel transit time on accuracy of video capsule endoscopy in evaluating suspected small bowel bleeding
作者机构：Internal MedicineEinstein Medical Center PhiladelphiaPhiladelphiaPA 19141United States Division of Gastrointestinal Diseases and HepatologyEinstein Medical Center PhiladelphiaPhiladelphiaPA 19141United States Department of Urban Health and NutritionLasalle UniversityPhiladelphiaPA 19141United States
出 版 物：《World Journal of Gastrointestinal Pharmacology and Therapeutics》 (世界胃肠药理与治疗学杂志（英文版）（电子版）)
年 卷 期：2022年第13卷第6期
页 面：88-95页
学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学]
主 题：Small bowel transit time Endoscopy Video capsule endoscopy Obscure bleed Small bowel Anemia
摘 要：BACKGROUND Obscure small bowel bleeding is defined as gastrointestinal bleeding(GIB)that is unidentifiable with esophagogastroduodenoscopy and a colonoscopy with video capsule endoscopy(VCE)being the next gold standard step for *** bowel transit time(SBTT)is a metric of a VCE study that is defined as the time the capsule takes to travel through the small *** To determine if SBTT within the VCE study,correlates to overall detection of obscure small bowel ***,we attempted to identify any existing correlation between SBTT and re-bleeding after a negative VCE *** This is a single center retrospective analysis of VCE studies performed for overt and occult GIB at Einstein Medical Center,Philadelphia,between 2015 and *** criteria primarily consisted of patients 18 years or older who had a VCE study done as part of the workup for a *** with incomplete VCEs,poor preparation,or with less than 6 mo of follow up were excluded.A re-bleeding event was defined either as overt or occult within a 6-mo *** rebleeding was defined as Visible melena or hematochezia with2 gm/dL drop in hemoglobin defined an overt re-bleeding event;whereas an unexplained2 gm/dL drop in hemoglobin with no visible bleeding defined an occult *** Results indicated that there was a significant and positive point biserial correlation between SBTT of 220 min and detection of a bleeding focus with a statistically significant p value of ***,the area under the curve was negligible when trying to identify a threshold time for SBTT to discriminate between risk of re-bleeding events after a negative *** In terms of SBTT and association with accuracy of VCE finding a bleeding focus,220 min was found to be adequate transit time to accurately find a bleeding focus,when *** was found that no threshold SBTT could be identified to help predict re-bleeding after a negative VCE.
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