Pharmacological and analytical aspects of alkannin/shikonin and their derivatives:An update from 2008 to 2022

作     者：Kirandeep Kaur Rashi Sharma Atamjit Singh Shivani Attri Saroj Arora Sarabjit Kaur Neena Bedi Kirandeep Kaur;Rashi Sharma;Atamjit Singh;Shivani Attri;Saroj Arora;Sarabjit Kaur;Neena Bedi

作者机构：Department of Pharmaceutical SciencesGuru Nanak Dev UniversityAmritsar 143005India Department of Botanical and Environmental SciencesGuru Nanak Dev UniversityAmritsar 143005India 

出 版 物：《Chinese Herbal Medicines》 (中草药（英文版）)

年 卷 期：2022年第14卷第4期

页      面：511-527页

学科分类：1008[医学-中药学(可授医学、理学学位)] 1007[医学-药学(可授医学、理学学位)] 1006[医学-中西医结合] 100602[医学-中西医结合临床] 10[医学] 

基　　金：Ministry of Education  India  MoE 

主　　题：alkannin naphthoquinones patents shikonin 

摘      要：Alkannin/shikonin(A/S)and their derivatives are naturally occurring naphthoquinones majorly found in Boraginaceae family *** are integral constituents of traditional Chinese medicine Zicao(roots of Lithospermum erythrorhizon).In last two decades significant increase in pharmacological investigations on alkannin/shikonin and their derivatives has been reported that resulted in discovery of their novel mechanisms in various diseases and *** review throws light on recently conducted pharmacological investigations on alkannin/shikonin and their derivatives and their *** analytical aspects are also discussed and brief summary of patent applications on inventions containing alkannin/shikonin and its derivatives is also provided.