Genitourinary melanoma:An overview for the clinician

作     者：Danielle K.DePalo Kelly M.Elleson Michael J.Carr Philippe E.Spiess Jonathan S.Zager Danielle K.DePalo;Kelly M.Elleson;Michael J.Carr;Philippe E.Spiess;Jonathan S.Zager

作者机构：Department of Cutaneous OncologyMoffitt Cancer CenterTampaFLUSA Department of SurgeryUniversity of LouisvilleLouisvilleKYUSA Department of Genitourinary OncologyMoffitt Cancer CenterTampaFLUSA 

出 版 物：《Asian Journal of Urology》 (亚洲泌尿外科杂志（英文）)

年 卷 期：2022年第9卷第4期

页      面：407-422页

核心收录：

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

基　　金：Novartis 

主　　题：Genitalia Female Male Melanoma Rare diseases Staging Treatment Urinary tract 

摘      要：Genitourinary (GU) melanoma is a rare presentation of melanoma accounting for approximately 0.5% of all *** melanomas include primary melanomas of the vulva,vagina,uterine cervix,ovary,penis,scrotum,urethra,bladder,ureter,and *** melanomas are often diagnosed in advanced stages and stigma is thought to contribute to delays in *** the likely diagnosing provider,it is imperative that dermatologists,urologists,and gynecologists are aware of these uncommon sites of *** there have been major advances in the treatment of melanomas as a whole in the last 10 years,their applications to GU melanomas have often been *** melanomas have not been included in many of the major phase II clinical trials which brought contemporary advanced treatments to market and the prognoses for GU melanomas remain *** to the rarity of GU melanomas,much of the literature provides gener alized recommendations across multiple different organs affected by GU melanomas or omits certain topics,making it difficult to appreciate the funda-mentals of the individual *** review aimed to provide background information on the pathogenesis and epidemiology of the different sites of GU melanomas and categorize data specific to the presentation,staging,treatment,and prognosis of each type of GU melanoma to guide the *** was also meant to encourage a multidisciplinary approach to the management of these patients as it spans the expertise of surgical oncologists,medical oncologists,radiation oncologist,dermatologists,urologists,and gynecologists.