A rare case of giant panda cancer:Pancreatic ductal adenocarcinoma

作     者：Yunsheng Wang Maohua Xia Xiangxiang Li Xinxin Guo Yan Lu Sufen Zhao Tianchun Pu Yunsheng Wang;Maohua Xia;Xiangxiang Li;Xinxin Guo;Yan Lu;Sufen Zhao;Tianchun Pu

作者机构：Wildlife Pathological diagnosis LaboratoryDepartment of Veterinary HospitalBeijing ZooBeijingChina Beijing Key Laboratory of Captive Wildlife TechnologiesBeijing ZooBeijingChina Wildlife Clinical LaboratoryDepartment of Veterinary HospitalBeijing ZooBeijingChina 

出 版 物：《Animal Models and Experimental Medicine》 (动物模型与实验医学（英文）)

年 卷 期：2022年第5卷第6期

页      面：582-586页

核心收录：

学科分类：090603[农学-临床兽医学] 09[农学] 0906[农学-兽医学] 

基　　金：Technology project of Beijing municipal administration center of parks Grant/Award Number:zx2021019 

主　　题：giant panda pancreatic ductal adenocarcinoma(PDAC) the pathological diagnosis of wild animals 

摘      要：Pancreatic ductal adenocarcinoma(PDAC)is a highly malignant cancer of the digestive system common among ***,it is rarely reported in wild *** 2018,a giant panda died in the Beijing *** subsequent histological observation of the pancreas,it was discovered that the glandular epithelial cells had lost the pancreatic acinar structure,tubular areas with obvious structure in the pancreas,and the ductal epithelium was substituted by high columnar mucus *** staining showed that there were several fibrous tissue proliferative reactions around the ductal adenocarcinoma and immunohistochemical staining revealed that CK7 and CK19 were positively expressed in the pancreatic ***,the pathological diagnosis indicated that the panda had *** this paper,the panda’s living conditions and pathological diagnosis results are examined,with the aim of providing a reference point for the future diagnosis of wild animal tumors.