Hearing Loss in Lassa Fever: A Systematic Review

作     者：Ethel Nkechi Chime Peter Ekpunobi Chime Jones Ndubuisi Nwosu Ethel Nkechi Chime;Peter Ekpunobi Chime;Jones Ndubuisi Nwosu

作者机构：Department of Otorhinolaryngology University of Nigeria Teaching Hospital Ituku-Ozalla Nigeria Department of Otorhinolaryngology Enugu State University of Science and Technology Teaching Hospital Parklane Nigeria Department of Medicine Enugu State University of Science and Technology Teaching Hospital Parklane Nigeria 

出 版 物：《Open Journal of Preventive Medicine》 (预防医学期刊（英文）)

年 卷 期：2022年第12卷第11期

页      面：239-247页

学科分类：1002[医学-临床医学] 100213[医学-耳鼻咽喉科学] 10[医学] 

主　　题：Hearing Loss Hearing Impairment Lassa Fever 

摘      要：Background: Lassa fever is a viral haemorrhagic fever associated with several complications which include hearing loss. Hearing loss in Lassa fever may become residual with its negative impact on the quality of life. Purpose: This paper is a review of various studies on Lassa fever related hearing loss. Methods: Systematic literature review was done on articles on Lassa fever patients and Lassa fever survivors. Relevant articles published in English between 1969 and 2021 were searched for using Google Scholar and PubMed databases. Eight studies which met the inclusion criteria were finally selected and included in the review. The variables of interest were extracted from the full-text articles. Results: Lassa fever related hearing loss occurs in both sexes and in all age groups. The incidence of self-reported hearing loss ranged from 12.5% to 30% with a mean of 17.6%. The incidence of audiometrically determined sensorineural hearing loss ranged from 13.5% to 29% with a mean of 22.1%. Hearing loss persisted in 64% of those that were followed up. Cases of hearing loss varied in severity, ranging from mild to profound. No successful specific treatment for Lassa fever related hearing loss was reported apart from hearing rehabilitation. Conclusion: Hearing loss among Lassa fever patients remains a major challenge. Lack of effective treatment for Lassa fever related hearing loss is a serious gap in the management of Lassa fever patients which should be addressed in future research.