Weakened humoral immune responses of inactivated SARS-CoV-2 vaccines in patients with solid tumors

作     者：Zhiwei Chen Peng Zhu Zuojin Liu Bin Zhu Guobing Yin Jia Ming Rui Song Qingbo Pan Tong Li Xingwei Jiang Bing Wang Shuaibin Liu Hongxing Cai Jingjie Wang Yuling Han Zijing Lin Yang Hong Min Chen Mingli Peng Lina Hu Dachuan Cai Hong Ren 

作者机构：Department of Infectious DiseasesKey Laboratory of Molecular Biology for Infectious Diseases(Ministry of Education)Institute for Viral Hepatitisthe Second Affiliated Hospital of Chongqing Medical UniversityChongqing 400010P.R.China Department of Gastrointestinal Surgerythe Second Affiliated Hospital of Chongqing Medical UniversityChongqing 400010P.R.China Department of Hepatobiliary Surgerythe Second Affiliated Hospital of Chongqing Medical UniversityChongqing 400010P.R.China Department of Thoracic and Cardiovascular Surgerythe Second Affiliated Hospital of Chongqing Medical UniversityChongqing 400010P.R.China Department of Breast and Thyroid Surgerythe Second Affiliated Hospital of Chongqing Medical UniversityChongqing 400010P.R.China Department of Gynaecology and ObstetricsReproductive Medicine Centerthe Second Affiliated Hospital of Chongqing Medical UniversityChongqing 400010P.R.China 

出 版 物：《Cancer Communications》 (癌症通讯（英文）)

年 卷 期：2023年第43卷第2期

页      面：280-284页

核心收录：

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

基　　金：the Ethics Committee of the Second Affiliated Hospital of Chongqing Medical University and conformed with the ethical guidelines of the Declaration of Helsinki(Ratification No.133/2022) Written informed consentwas obtained fromall the participants.This study has been registered at ClinicalTrials.gov(NCT05043246) 

主　　题：patients vaccines humoral 

摘      要：Dear Editor Coronavirus disease 19(COVID-19),caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),remains a *** patients have a higher risk of poor outcomes for SARS-CoV-2 infection than the general population[1].Vaccines were shown to effectively prevent SARS-CoV-2 infection,severe disease progression,and *** SARS-CoV-2 vaccines(BBIBPCorV and CoronaVac)have been approved and widely used in China,with the former shown to be more effective than the latter[2].Hence,there is an urgent need to investigate the safety and humoral immune responses of inactivated vaccines in cancer patients.