Positive association between triglyceride glucose index and central systolic blood pressure among hypertensive adults

作     者：Li WANG Tian-Yu CAO Jin-Qiao LI Cong-Cong DING Jun-Pei LI Hua-Bo YING Li-Shun LIU Xiao HUANG Li WANG;Tian-Yu CAO;Jin-Qiao LI;Cong-Cong DING;Jun-Pei LI;Hua-Bo YING;Li-Shun LIU;Xiao HUANG

作者机构：Department of Nephrologythe Fourth Hospital of Harbin Medical UniversityHarbinChina Biological Anthropo-logyUniversity of California Santa BarbaraCaliforniaUSA Department of Urology SurgeryGraduate School of the Fourth Hospital of Harbin Medical UniversityHarbinChina Department of Cardiologythe Second Affiliated Hospi-tal of Nanchang UniversityNanchangChina Institute of BiomedicineAnhui Medical UniversityHefeiChina Instit-ute of Biomedical and Health EngineeringGraduate School at ShenzhenTsinghua UniversityShenzhenChina Shen-zhen Evergreen Medical InstituteShenzhenChina 

出 版 物：《Journal of Geriatric Cardiology》 (老年心脏病学杂志（英文版）)

年 卷 期：2022年第19卷第10期

页      面：753-760,I0002页

核心收录：

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

基　　金：supported by the National Natural Science Foundation of China(No.81960074) the Key R&D Projects,Jiangxi(20203BBGL73173) the Pro-ject of Jiangxi Provincial Health Commission(No.202130440) 

主　　题：hypertensive elevated systolic 

摘      要：BACKGROUND While studies have suggested the association between triglyceride-glucose(TyG)index,a reliable surrogate for insulin resistance and hypertension data are limited to the correlation of TyG and central blood *** study aims to test the hypothesis that a higher TyG index is associated with elevated central systolic blood pressure(cSBP).METHODS A total of 9249 Chinese hypertensive adults from the H-type Hypertension and Stroke Prevention and Control Project were analyzed in this *** was measured noninvasively using an A-Pulse CASPro *** index was calculated as ln[fasting triglycerides(mg/dL)×fasting glucose(mg/dL)/2].Smoothing curve and multivariate linear regression models[beta coefficient(β)with 95%CI]were applied to analyze the association between TyG index and *** analyses were conducted to explore potential modifications to such a *** The overall mean TyG index is 8.8±0.7,and the total mean cSBP is 131.3±12.8 *** index was observed to be independently and positively associated with cSBP among the total population(β=0.92,95%CI:0.53–1.31,P0.001),and participants who do not use antihypertensive drugs(β=1.03,95%CI:0.46–1.60,P0.001),which is in accordance with the result of the smoothing *** association between TyG index and cSBP appears robust in all tested *** TyG index is positively and independently associated with cSBP among hypertensive *** study result suggests that TyG index might serve as an effective marker for vascular function.