Methotrexate Treatment of Ectopic Pregnancy: Prognosis at Senlis Hospital

作     者：Kossi Edem Logbo-Akey Kignomon Bingo M’bortche Pierre Yendoubé Kambote Dédé Régine Diane Ajavon Kibandou Noe Patidi Koko Gueze Abdoul-Samadou Aboubakari Kossi Edem Logbo-Akey;Kignomon Bingo M’bortche;Pierre Yendoubé Kambote;Dédé Régine Diane Ajavon;Kibandou Noe Patidi;Koko Gueze;Abdoul-Samadou Aboubakari

作者机构：Department of Gynecology and Obstetrics of the University Hospital of Kara University of Kara Kara Togo Togolese Association for Family Welfare (ATBEF) Clinic University of Lomé Lomé Togo Department of Gynecology and Obstetrics of the Regional Hospital Center of Tomdé University of Kara Kara Togo Department of Gynecology and Obstetrics of the University Hospital Sylvanus Olympio University of Lome Lome Togo 

出 版 物：《Open Journal of Obstetrics and Gynecology》 (妇产科期刊（英文）)

年 卷 期：2022年第12卷第10期

页      面：1086-1091页

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主　　题：Ectopic Pregnancy Methotrexate Prognosis 

摘      要：Introduction: Ectopic pregnancy is dreadful and can lead to the death of the patient if it is ignored. Diagnosed early, it offers the possibility of medical treatment with methotrexate. Objective: To describe the prognosis of ectopic pregnancies treated methotrexate. Patients and Methods: Retrospective study of the management of ectopic pregnancy by Methotrexate at Senlis hospital from June 2020 to May 2021 were included in the study, patients with a Fernandez score of less than 13, and having received Methotrexate as first-line treatment. Data were collected using gynecological emergency admission registers, and telephone interviews. Results: 35 cases were identified. The average age of the patients was 32 years old. Forty-nine percent were smokers. The mean gestational age was 5 weeks + 2 days. The diagnosis was made in all of our patients with the combination of the kinetics of ß-hcg and vaginal ultrasound. The size of adnexal mass was less than 4 cm with an average size of 20 mm. The average value of ß-hcg was 1405 IU/L. All patients had received a single dose of methotrexate 1 mg/kg intramuscularly. A second dose was administered to 17.1% of patients for stagnation or re-ascension of the ß-hcg level. The success rate was 91.4%. Thirty percent were obtained spontaneous intra uterine pregnancy, the first year following methotrexate treatment. Conclusion: The success rate of medical treatment for ectopic pregnancy is high in terms of meeting the eligibility criteria for treatment. The subsequent prognosis of fertility is generally preserved.