An updated study of traditional medicines to the era of 1,3,4 oxadiazole derivatives for malaria treatment
作者机构：Department of Pharmaceutical SciencesMaharishi Dayanand UniversityRohtak 124001HaryanaIndia Department of Pharmaceutical SciencesChaudhary Bansi Lal UniversityBhiwani 127021HaryanaIndia.
出 版 物：《Traditional Medicine Research》 (TMR传统医学研究)
年 卷 期：2023年第8卷第1期
页 面：36-42页
学科分类：1007[医学-药学(可授医学、理学学位)] 1002[医学-临床医学] 10[医学]
主 题：antimalarial Plasmodium falciparum 1,3,4 oxadiazoles traditional medicines
摘 要：Discovering potent drug candidates requires new antimalarial *** this reason,antimalarial drug researchers focus on developing new drug candidates on promising *** the identification of these targets,a basic understanding of the metabolism and biochemical processes of malaria parasites such as Plasmodium falciparum can prove ***,malarial resistant parasites are becoming more and more significant issues as antimalarial medications *** drugs are becoming increasingly resistant,thus the search for new molecules is very important *** based combination therapies are becoming more popular for treating *** will ultimately lead to the selection of resistance due to their extensive and indiscriminate *** artemisinin-based combination therapies are therefore *** is an interest in finding suitable antimalarial compounds based on their potential effectiveness against *** potential activity of 1,3,4 oxadiazole analogues against malarial infections is a major draw of the search for suitable antimalarial *** review identifies existing antimalarial drugs that have own therapeutic effects and evaluating their feasibility for developing novel synthetic antimalarial derivatives.
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