Advances in the research on the biological effects of heavy-ion radiation

作     者：DongJuancong ZuoYahui Dong Juancong;Zuo Yahui

作者机构：030006 Taiyuan China Institute for Radiation Protection 

出 版 物：《中华放射医学与防护杂志》 (Chinese Journal of Radiological Medicine and Protection)

年 卷 期：2015年第35卷第1期

页      面：35-39,72页

核心收录：

学科分类：1006[医学-中西医结合] 1002[医学-临床医学] 10[医学] 100602[医学-中西医结合临床] 

基　　金：supported by a grant from National Project on Basic Research of China during the Twelfth Five-Year Plan Period 

主　　题：临床 医学 诊断 放射医学 

摘      要：Heavy iron radiation offer significant advantages for the treatment of deep-seated local tumors in comparison to conventional megavolt photon *** a plethora of malignancies,current radiotherapy using photons or protons yields marginal benefits in local control and *** the last decade,heavy- ion radiotherapy facilities have slowly been constructed in Europe and Asia,demonstrating favorable results for many of the malignancies for which conventional radiotherapy yields poor ***,for a radiobiological perspective,the mechanism whereby heavy ion works in overcoming radio-resistance and the mechanismwherebyradiotherapycombinedwith systemic therapies extends local control and survival are not yet fully *** radiation,comprised of energetic protons and heavy nuclei,has been shown to cause distinct biological damage compared with radiation on earth,leading to large uncertainties in the projection of cancer and other healthrisks,andobscuringevaluationofthe effectiveness of possible *** in the field of biological effects of heavy charged particles is needed for both heavy-ion therapy and protection from the exposure to galactic cosmic radiation in long- term manned space *** article reviews the progress in the research of the biological effects of heavy-ionradiationinspaceexplorationand radiotherapy,and the open questions that remain to be addressed.